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isopenicillin N acyltransferase activity

Known as: isopenicillin-N N-acyltransferase activity, acyl-CoA:isopenicillin N N-acyltransferase activity, isopenicillin-N acyltransferase activity 
Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate. [EC:2.3.1.164, MetaCyc:2.3.1.164… Expand
National Institutes of Health

Papers overview

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2017
2017
Abstract Isopenicillin N synthase (IPNS) catalyses the four‐electron oxidation of a tripeptide, l‐δ‐(α‐aminoadipoyl)‐l‐cysteinyl… Expand
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2007
2007
The Drosophila mutant tan (t) shows reciprocal pigmentation defects compared with the ebony (e) mutant. Visual phenotypes… Expand
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2007
2007
A carbocyclic analogue of the beta-lactam antibiotic isopenicillin N (IPN) has been synthesised and cocrystallised with… Expand
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2004
2004
SummaryAmmonium and asparagine produced a concentration-dependent reduction of cephamycin C biosynthesis by Streptomyces… Expand
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2003
2003
Isopenicillin N synthase (IPNS) catalyses conversion of the linear tripeptide delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-valine… Expand
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2000
2000
Flavanone 3beta-hydroxylase (FHT) catalyzes a pivotal reaction in the formation of flavonoids, catechins, proanthocyanidins and… Expand
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Review
1994
Review
1994
The genespcbAB,pcbC andpenDE encoding the enzymes (α-aminoadipyl-cysteinyl-valine synthetase, isopenicillin N synthase and… Expand
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1993
1993
The isopenicillin-N acyltransferase of Penicillium chrysogenum catalyzes the conversion of the biosynthetic intermediate… Expand
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1979
1979
1. delta-(L-alpha-Amino[4,5-3H]adipyl)-L-cysteinyl-D-[4,4-3H]valine has been synthesized from its constituent amino acids, the L… Expand
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1975
1975
1. Phenoxymethylpenicillin sulphoxide 4-methoxybenzyl ester was labelled with 3H in its 2-beta-methyl group. Its specific… Expand
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