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isomethadone

Known as: 6-(dimethylamino)-5-methyl-4,4-diphenyl-3-hexanone 
National Institutes of Health

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Methadone

Papers overview

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1982
1982
Synthesis, X-ray crystallographic determination, and opioid activity of erythro-5-methylmethadone enantiomers. Evidence which suggests that mu and delta opioid receptors possess different…
Enantiomers of erythro-5-methylmethadone (3) were synthesized from optical antipodes of erythro-3-(dimethyl-amino)-2-butanol. X… 
1976
1976
Stereochemical studies on medicinal agents. 21. Investigation of the role of conformational factors in the action of diphenylpropylamines. Synthesis and analgetic potency of 5-methylmethadone…
The synthesis of racemic threo- and erythro-5-methylmethadone (3a and 3b, respectively) was carried out and the solution… 
1974
1974
Stereochemical studies on medicinal agents. 16. Conformational studies of methadone and isomethadone utilizing circular dichroism and proton magnetic resonance.
1973
1973
[Stereoselectivity of the reduction of isomethadone (author's transl)].
1971
1971
Identification and quantitative determination of some metabolites of methadone, isomethadone and normethadone
Isomethadone and normethadone are metabolized by microsomal preparations of guinea‐pig liver to yield 2‐ethyl‐1,4‐dimethyl‐3,3… 
1967
1967
Analgesically active basic anilides: stereospecificity and structure of the basic group
  • A. F. CASYM. Hassan
  • The Journal of pharmacy and pharmacology
  • 1967
  • Corpus ID: 38501282
The synthesis of (RS)‐, (R)‐ and (S)‐N‐(2‐dimethylaminopropyl)propionanilide and the benzylmethylamino‐ analogues of methadone… 
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