isomethadone

Known as: 6-(dimethylamino)-5-methyl-4,4-diphenyl-3-hexanone

National Institutes of Health

Papers overview

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1982

1982

Synthesis, X-ray crystallographic determination, and opioid activity of erythro-5-methylmethadone enantiomers. Evidence which suggests that mu and delta opioid receptors possess different…

Enantiomers of erythro-5-methylmethadone (3) were synthesized from optical antipodes of erythro-3-(dimethyl-amino)-2-butanol. X…

1976

1976

Stereochemical studies on medicinal agents. 21. Investigation of the role of conformational factors in the action of diphenylpropylamines. Synthesis and analgetic potency of 5-methylmethadone…

The synthesis of racemic threo- and erythro-5-methylmethadone (3a and 3b, respectively) was carried out and the solution…

1974

1974

Stereochemical studies on medicinal agents. 16. Conformational studies of methadone and isomethadone utilizing circular dichroism and proton magnetic resonance.

1973

1973

[Stereoselectivity of the reduction of isomethadone (author's transl)].

1967

1967

Analgesically active basic anilides: stereospecificity and structure of the basic group

A. CasyM. Hassan
The Journal of pharmacy and pharmacology
1967
Corpus ID: 38501282

The synthesis of (RS)‐, (R)‐ and (S)‐N‐(2‐dimethylaminopropyl)propionanilide and the benzylmethylamino‐ analogues of methadone…