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Isoglobotrihexosylceramide (iGb3) has been identified as a potent CD1d‐presented self‐antigen for mouse invariant natural killer… Expand Puga Yung GL, Li Y, Borsig L, Millard A‐L, Karpova MB, Zhou D, Seebach JD. Complete absence of the αGal xenoantigen and… Expand Certain glycolipid antigens for natural killer T (NKT) cells can direct the overall cytokine balance of the immune response… Expand Gaucher disease (GD) is associated with upregulation of CD1d and MHC-class II expression by monocytes. While the physiological… Expand Glycosphingolipids serve as ligands for receptors involved in signal transduction and immune recognition, as exemplified by… Expand CD1d-restricted natural killer T (NKT) cells, expressing the invariant T cell antigen receptor (TCR) chain encoded by Vα14-Jα18… Expand Development of invariant natural killer T (iNKT) cells requires the presentation of lipid ligand(s) by CD1d molecules in the… Expand Invariant natural killer T (iNKT) cells are innate T lymphocytes that express T cell receptors binding to exogenous and… Expand Isoglobotrihexosylceramide (iGb3) is an endogenous antigen of mammalian cells and can stimulate invariant natural killer T (iNKT… Expand Glycoceramides can activate NKT cells by binding with CD1d to produce IFN-gamma, IL-4, and other cytokines. An efficient… Expand