FAQ

isocitrate lyase activity

Known as: isocitritase activity, threo-DS-isocitrate glyoxylate-lyase activity, isocitrase activity 
Catalysis of the reaction: isocitrate = glyoxylate + succinate. [EC:4.1.3.1, RHEA:13248]

Topic mentions per year

Topic mentions per year

1962-2016
0519622016

Papers overview

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2011
2011
Phosphorylation is the major mechanism regulating isocitrate lyase activity in Paracoccidioides brasiliensis yeast cells.
The glyoxylate cycle plays an essential role for anaplerosis of oxaloacetate during growth of microorganisms on carbon sources… (More)
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2010
2010
Influence of RpoN on isocitrate lyase activity in Pseudomonas aeruginosa.
Pseudomonas aeruginosa is the major aetiological agent of chronic pulmonary infections in patients with cystic fibrosis (CF). The… (More)
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2008
2008
Virulence determinants from a cystic fibrosis isolate of Pseudomonas aeruginosa include isocitrate lyase.
Chronic lung infections caused by Pseudomonas aeruginosa are the leading cause of morbidity and mortality for cystic fibrosis (CF… (More)
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2006
2006
Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development.
Invasive aspergillosis, caused by Aspergillus fumigatus, is a severe systemic infection in immunocompromised patients. New drug… (More)
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2005
2005
L-malyl-coenzyme A/beta-methylmalyl-coenzyme A lyase is involved in acetate assimilation of the isocitrate lyase-negative bacterium Rhodobacter capsulatus.
Cell extracts of Rhodobacter capsulatus grown on acetate contained an apparent malate synthase activity but lacked isocitrate… (More)
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Highly Cited
1999
Highly Cited
1999
Characterization of activity and expression of isocitrate lyase in Mycobacterium avium and Mycobacterium tuberculosis.
Analysis by two-dimensional gel electrophoresis revealed that Mycobacterium avium expresses several proteins unique to an… (More)
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1996
1996
Metabolic activities of metronidazole-sensitive and -resistant strains of Helicobacter pylori: repression of pyruvate oxidoreductase and expression of isocitrate lyase activity correlate with…
In this study, we compared metronidazole (Mtz)-sensitive and -resistant strains of Helicobacter pylori for metabolic differences… (More)
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1994
1994
Characterization of the isocitrate lyase gene from Corynebacterium glutamicum and biochemical analysis of the enzyme.
Isocitrate lyase is a key enzyme in the glyoxylate cycle and is essential as an anaplerotic enzyme for growth on acetate as a… (More)
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1980
1980
Genetic regulation of isocitrate lyase activity in Aspergillus nidulans.
The formation of the glyoxylate cycle enzymes isocitrate lyase and malate synthase is strongly regulated in Aspergillus nidulans… (More)
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1968
1968
Genetic control of isocitrate lyase activity in Escherichia coli.
Isocitrate lyase (EC 4.1.3.1) plays a necessary role in the growth of Escherichia coli on acetate as sole carbon source (1… (More)
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