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isocitrate dehydrogenase (NADP+) activity

Known as: isocitrate (NADP) dehydrogenase activity, isocitrate:NADP+ oxidoreductase (decarboxylating), NADP-dependent isocitrate dehydrogenase activity 
Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+. [EC:1.1.1.42]
National Institutes of Health

Papers overview

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2007
2007
Phosphoenolpyruvate inhibited Escherichia coli NADP-isocitrate dehydrogenase allosterically (Ki of 0.31 mM) and isocitrate lyase… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT We identified chnR, a gene encoding an AraC-XylS type of transcriptional activator that regulates the expression ofchnB… Expand
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1984
1984
The use of the antineoplastic agent adriamycin is limited by its cardiotoxicity. The mechanism of cardiotoxicity has been… Expand
Highly Cited
1983
Highly Cited
1983
Antibodies against purified NADP-isocitrate dehydrogenase from pig liver cytosol and pig heart were raised in rabbits. The… Expand
Highly Cited
1977
Highly Cited
1977
Coho salmon (Oncorhynchus kisutch), 8 to 18 months of age, were maintained in culture tanks and were fed three semipurified diets… Expand
Highly Cited
1974
Highly Cited
1974
  • M. S. Patel
  • Journal of neurochemistry
  • 1974
  • Corpus ID: 7258545
To evaluate the relative significance of CO2‐fixing enzymes in the metabolism of rat brain, the subcellular distribution of… Expand
1973
1973
Abstract Biochemical pathways of fatty acid synthesis in sheep mammary tissue were investigated. Ewes were sacrificed (3 to 4 wk… Expand
Highly Cited
1971
Highly Cited
1971
1. The incorporation of [U-(14)C]glucose into several lipid components of lung and liver slices, and the activities of glucose 6… Expand
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1971
1971
Abstract : Highly puridied NADP(+)-linked isocitrate dehydrogenase was X-irradiated in dilute aqueous solution and proved to be… Expand
1970
1970
1. Superovulated rat ovary was found to contain high activities of NADP-malate dehydrogenase and NADP-isocitrate dehydrogenase… Expand