isoaurostatin
National Institutes of Health
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Isoaurostatin A (IAS-A) isolated from Thermomonospora alba showed weak inhibition against topoisomerase (topo) I (IC(50… Expand A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic… Expand The spectroscopic parameters used to assign the structure to isoaurostatin (4',6-dihydroxyisoaurone), a metabolite isolated from… Expand A novel inhibitor of topoisomerase I designated as isoaurostatin (1) was isolated from the culture filtrate of Thermomonospora… Expand