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isoaurostatin

 
National Institutes of Health

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2 relations

Broader (2)

BenzofuransTopoisomerase II Inhibitors

Papers overview

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2005
2005
Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships.
Isoaurostatin A (IAS-A) isolated from Thermomonospora alba showed weak inhibition against topoisomerase (topo) I (IC(50… Expand
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2005
2005
A new synthesis of isoaurones: cytotoxic activity of compounds related to the alleged structure of isoaurostatin.
A new synthesis of isoaurones related to the alleged structure of isoaurostatin, via Heck intramolecular cyclization of cinnamic… Expand
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2005
2005
Reinterpretation of the evidence for the structure of isoaurostatin.
The spectroscopic parameters used to assign the structure to isoaurostatin (4',6-dihydroxyisoaurone), a metabolite isolated from… Expand
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2001
2001
Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba.
A novel inhibitor of topoisomerase I designated as isoaurostatin (1) was isolated from the culture filtrate of Thermomonospora… Expand
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