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irosustat
Known as:
6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta-(c)(1)benzopyran-3-O-sulfamate
, STX 64
Steroid sulfatase inhibitor BN 83495 selectively binds to and inhibits steroid sulfatase (STS), which may inhibit the production of locally active…
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National Institutes of Health
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Related topics
Related topics
4 relations
667 coumate
NCIt Antineoplastic Agent Terminology
Narrower (1)
BN83495
Broader (1)
Sulfonic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
The effects of the first in class steroid sulfatase inhibitor Irosustat on FLT uptake and Ki67 in estrogen receptor positive early breast cancer: Results of the perioperative IPET study.
C. Palmieri
,
Richard Szydlo
,
+11 authors
L. Kenny
2016
Corpus ID: 81906316
e23140Background: The steroid sulfatase (STS) pathway is involved in oestrogen biosynthesis. Irosustat is a 1st generation…
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2013
2013
In vitro metabolism and drug-drug interaction potential of irosustat, a steroidal sulfatase inhibitor
Verònica Ventura Ventanachs
2013
Corpus ID: 83403553
Irosustat is a first-generation, irreversible, steroid sulfatase inhibitor currently in development for hormone-dependent cancer…
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2011
2011
In Vitro Metabolism of Irosustat, a Novel Steroid Sulphatase Inhibitor: Inter-Species Comparison, Metabolite Identification and Metabolic Enzyme Identification
V. Ventura
,
J. Sola
,
+9 authors
Spain
2011
Corpus ID: 263158493
Irosustat is a novel steroid sulphatase inhibitor for hormone-dependent cancer therapy. Its structure is a tricyclic coumarin…
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