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iron bleomycin

 
National Institutes of Health

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2001
2001
The hypothesis was investigated that axial ligands bound to Fe(III)-bleomycin [Fe(III)Blm] are destabilized at specific 5… Expand
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1998
1998
The transposon Tn5 ble gene and the Escherichia coli alkylation-inducible aidC locus are co-operatively involved in the… Expand
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1994
1994
DNA strand scission initiated by bleomycin is a multistep process. Three C-C or C-O bonds are broken, releasing base propenal, a… Expand
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1994
1994
0.8 min) concurrently with base propenal. Since strand scis- sion precedes phosphomonoester formation, strand scission cannot… Expand
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1994
1994
Studies with Euglena gracilis and HL-60 cells have assessed the need for intracellular iron in the mechanisms of inhibition of… Expand
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1991
1991
The reaction of ferrous bleomycin with dioxygen is reexamined to clarify whether radical species derived from molecular oxygen… Expand
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1990
1990
A comparison of the intracellular DNA strand scission activities of the antitumor drug bleomycin, three of its metal complexes… Expand
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1984
1984
In the presence of NADPH and O2, NADPH-cytochrome P-450 reductase was found to activate Fe(III)-bleomycin A2 for DNA strand… Expand
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1983
1983
Using Mössbauer spectroscopy, we have examined iron-bleomycin in various oxidation states and in complexes with dioxygen or… Expand
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1979
1979
Abstract Iron(III)bleomycin undergoes a redox reaction with thiols. Evidence from epr and UV-visible absorbance spectra indicate… Expand
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