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irbesartan
Known as:
irbesartan [Chemical/Ingredient]
, 2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one
, 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-
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A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II…
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National Institutes of Health
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Related topics
Related topics
23 relations
Angiotensin 2 Receptor Antagonists [MoA]
Angiotensin 2 Type 1 Receptor Antagonists [MoA]
CYP2C9 protein, human
Decreased Blood Pressure [PE]
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Broader (4)
Angiotensin II Type 1 Receptor Blockers
Antihypertensive Agents
Biphenyl Compounds
Tetrazoles
Narrower (4)
Avalide
Avapro
BMS 186295
SR 47436
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
A REVIEW ON IRBESARTAN CO ADMINISTERED WITH ATORVASTATIN FOR THE TREATMENT OF CARDIAC RISK
P. Virani
,
Rajanit Sojitra
,
H. Raj
,
V. Jain
2014
Corpus ID: 55878240
Hypertension and Hypercholesterolemia are a major public health problem in the developedCountries. .in recently Hypertension and…
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2012
2012
Enhancement of Dissolution Rate of Irbesartan by Chitosan based Crystal Engineering Technique
A. Shete
,
A. V. Yadav
,
M. S. Murthy
2012
Corpus ID: 51946186
0chitosan on drug crystals. The precipitate obtained was filtered through Whatmann No. 1 filter paper using vacuum filtration…
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2011
2011
Septrofluorometric, Spectrophotometric and LC Determination of Irbesartan
R. El-Bagary
,
H. Hashem
,
W. Ebeid
2011
Corpus ID: 56395735
Simple, accurate and precise spectroflourimetric, spectrophotometric and LC methods have been developed and validated for the…
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2010
2010
[Effect of irbesartan of the function of hemocoagulative component of hemostasis in patients with arterial hypertension during metabolic syndrome].
V. Simonenko
,
I. Medvedev
,
V. Tolmachev
Klinicheskaia meditsina
2010
Corpus ID: 148206
The aim of the study was to assess effects of irbesartan on disturbed platelet hemostasis in patients with arterial hypertension…
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2010
2010
Curcumin/Irbesartan Combination Improves Insulin Sensitivity and Ameliorates Serum Pro-inflammatory Cytokines levels in Diabetes Rat model
M. Mohamed
2010
Corpus ID: 12770316
To evaluate the impact of chronic administration of an angiotensin II receptor antagonist (Irbesartan) and/or curcumin on fasting…
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2009
2009
The ACTIVE pursuit of stroke prevention in patients with atrial fibrillation.
A. Go
New England Journal of Medicine
2009
Corpus ID: 27421180
Approximately 1% of Americans have atrial fibrillation, and the prevalence of this arrhythmia increases sharply with older age…
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2004
2004
新規アンジオテンシンII拮抗薬オルメサルタン メドキソミル（オルメテック®）の薬理特性と臨床効果
T. Sada
,
M. Mizuno
2004
Corpus ID: 24930464
オルメサルタン メドキソミル（オルメテック®）はプロドラッグタイプのアンジオテンシンII（AII）受容体拮抗薬（ARB）であり，消化管で吸収された後，速やかに脱エステル化を受け，活性体オルメサルタンに変換され薬効を示す．オルメサルタンはチトクロムP450…
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2003
2003
Estimation of plasma irbesartan using HPTLC and HPLC
R. Sane
,
M. Francis
,
S. Pawar
2003
Corpus ID: 100368853
A selective and sensitive HPLC and a HPTLC method for the determination of irbesartan in human plasma were developed. Irbesartan…
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2002
2002
Low-Dose Combination Therapy with Perindopril and Indapamide Compared with Irbesartan
Trefor Owen Morgan
,
A. Anderson
2002
Corpus ID: 71223332
AbstractIntroduction: A study was undertaken in patients with essential hypertension to compare, by ambulatory blood pressure…
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2002
2002
Determination of irbesartan in pharmaceutical dosage forms by HPTLC
R. Sane
,
M. Francis
,
S. Pawar
2002
Corpus ID: 99333836
A stability-indicating HPTLC method was developed to analyse irbesartan in tablet dosage form. Irbesartan and the internal…
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