irbesartan

Known as: irbesartan [Chemical/Ingredient], 2-n-butyl-3-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1,3-diazaspiro(4,4)non-1-en-4-one, 1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)- 
A nonpeptide angiotensin II antagonist with antihypertensive activity. Irbesartan selectively and competitively blocks the binding of angiotensin II… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND The risk of cardiovascular events among patients with atrial fibrillation is high. We evaluated whether irbesartan, an… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND The metabolic syndrome is associated with increased angiotensin II activity, induction of a proinflammatory and… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Postprandial hypertriglyceridemia and hyperglycemia are considered risk factors for cardiovascular disease. Evidence… (More)
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Highly Cited
2005
Highly Cited
2005
Elevated arterial pressure enhances the risk for cardiovascular (CV) events in patients with diabetic nephropathy. The optimal BP… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND It remains controversial whether specific blockade of the renin-angiotensin system confers superior… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Data from studies of angiotensin-converting enzyme inhibitors provide evidence that the renin-angiotensin-aldosterone… (More)
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Highly Cited
2001
Highly Cited
2001
  • DMUND, L. J., +11 authors TKINS
  • 2001
A BSTRACT Background It is unknown whether either the angiotensin-II–receptor blocker irbesartan or the calcium-channel blocker… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Microalbuminuria and hypertension are risk factors for diabetic nephropathy. Blockade of the renin-angiotensin system… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND It is unknown whether either the angiotensin-II-receptor blocker irbesartan or the calcium-channel blocker amlodipine… (More)
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