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iodoaminopotentidine

Known as: Benzamide, 4-amino-N-(2-(((cyanoamino)((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)methylene)amino)ethyl)-3-iodo- 
 
National Institutes of Health

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Broader (1)

Guanidines

Papers overview

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1999
1999
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder.
Histamine H2 receptor-mediated responses were examined on cholecystokinin-octapeptide (CCK-8)-precontracted guinea pig… Expand
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1998
1998
Evidence of H3 receptor inhibition by iodoaminopotentidine in the guinea pig ileum.
Activation of histamine H3 receptors by histamine (0.1 to 10 microM), (R)alpha-methylhistamine and N(alpha)-methylhistamine (0.01… Expand
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1996
1996
Cardiac and gastric effects of histamine H2 receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity.
1. A series of histamine H2 receptor antagonists with different lipophilicity were tested in cardiac and gastric assays in order… Expand
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1992
1992
Pharmacological characterization and autoradiographic localization of histamine H2 receptors in human brain identified with [125I]iodoaminopotentidine.
125I-Aminopotentidine (125I-APT), a reversible probe of high specific radioactivity and high affinity and selectivity for the H2… Expand
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1992
1992
Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
The synthesis and biological evaluation of a new class of histamine H2 antagonists with N-cyano-N'-[omega-[3-(1-piperidinylmethyl… Expand
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1990
1990
Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H2 receptor using [125I]iodinated probes.
Iodoaminopotentidine (I-APT)--i.e., N-[2-(4-amino-3-iodobenzamido)ethyl]-N'-cyano-N''-(3-[3- (1-piperidinylmethyl)phenoxy]propyl… Expand
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