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iodoaminopotentidine

Known as: Benzamide, 4-amino-N-(2-(((cyanoamino)((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)methylene)amino)ethyl)-3-iodo- 
National Institutes of Health

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Broader (1)

Guanidines

Papers overview

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1999
1999
Effects of histamine H2 receptor agonists and antagonists on the isolated guinea pig gallbladder
Abstract— Histamine H2 receptor‐mediated responses were examined on cholecystokinin‐octapeptide (CCK‐8)‐precontracted guinea pig… Expand
1998
1998
Evidence of H3 receptor inhibition by iodoaminopotentidine in the guinea pig ileum.
Activation of histamine H3 receptors by histamine (0.1 to 10 microM), (R)alpha-methylhistamine and N(alpha)-methylhistamine (0.01… Expand
1996
1996
Cardiac and gastric effects of histamine H2 receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity
1 . A series of histamine H2 receptor antagonists with different lipophilicity were tested in cardiac and gastric assays in order… Expand
Highly Cited
1992
Highly Cited
1992
Pharmacological Characterization and Autoradiographic Localization of Histamine H2 Receptors in Human Brain Identified with [125I]Iodoaminopotentidine
125I‐Aminopotentidine (125I‐APT), a reversible probe of high specific radioactivity and high affinity and selectivity for the H2… Expand
1992
1992
Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
The synthesis and biological evaluation of a new class of histamine H2 antagonists with N-cyano-N'-[omega-[3-(1-piperidinylmethyl… Expand
Highly Cited
1990
Highly Cited
1990
Reversible and irreversible labeling and autoradiographic localization of the cerebral histamine H2 receptor using [125I]iodinated probes.
Iodoaminopotentidine (I-APT)--i.e., N-[2-(4-amino-3-iodobenzamido)ethyl]-N'-cyano-N''-(3-[3- (1-piperidinylmethyl)phenoxy]propyl… Expand
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