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iodoacetanilide

 
National Institutes of Health

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Acetanilides

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2013
2013
Quantitative protein analysis using (13)C7-labeled iodoacetanilide and d5-labeled N-ethylmaleimide by nano liquid chromatography/nanoelectrospray ionization ion trap mass spectrometry.
We have developed a methodology for quantitative analysis and concurrent identification of proteins by the modification of… Expand
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2012
2012
Peptide peak intensities enhanced by cysteine modifiers and MALDI TOF MS.
Two cysteine-specific modifiers we reported previously, N-ethyl maleimide (NEM) and iodoacetanilide (IAA), have been applied to… Expand
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2009
2009
Synthesis of 13C7-labeled iodoacetanilide and application to quantitative analysis of peptides and a protein by isotope differential mass spectrometry.
(13)C(7)-Labeled iodoacetanilide has been synthesized for specific labeling of sulfhydryl groups of cysteine residues and has… Expand
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Highly Cited
2008
Highly Cited
2008
Cysteine pK(a) values for the bacterial peroxiredoxin AhpC.
Salmonella typhimurium AhpC is a founding member of the peroxiredoxin family, a ubiquitous group of cysteine-based peroxidases… Expand
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2008
2008
Electrospray ionization mass spectroscopic analysis of peptides modified with N-ethylmaleimide or iodoacetanilide.
The cysteine-specific modifiers we reported previously, N-ethylmaleimide (NEM) and iodoacetanilide (IAA), have been applied to… Expand
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2008
2008
Isotope-coded, iodoacetamide-based reagent to determine individual cysteine pK(a) values by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Cysteine reactivity in enzymes is imparted to a large extent by the stabilization of the deprotonated form of the reduced… Expand
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2006
2006
Quantitative proteome analysis using D-labeled N-ethylmaleimide and 13C-labeled iodoacetanilide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
A new methodology for quantitative analysis of proteins is described, applying stable-isotope labeling by small organic molecules… Expand
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2004
2004
N-t-butyliodoacetamide and iodoacetanilide: two new cysteine alkylating reagents for relative quantitation of proteins.
The synthesis and application of two new alkylating reagents, N-tert-butyl-2-iodoacetamide (N-t-butyliodoacetamide) and 2-iodo-N… Expand
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2003
2003
Synthesis of 13C-labeled iodoacetanilide and application to quantitative peptide analysis by isotope differential mass spectrometry.
13C-Labeled and unlabeled iodoacetanilides have been synthesized for covalent modification of the sulfhydryl groups of cysteine… Expand
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1979
1979
Deuterated iodoacetanilide: a covalent protein label for neutron scattering studies.
A simple preparation of a deuterated alkylating reagent is described. Its reaction with the beta 93-SH groups of hemoglobin was… Expand
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