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interleukin-21 production

Known as: IL-21 production 
The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or… 
National Institutes of Health

Papers overview

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2019
2019
Interleukin-21 is a common γ-chain cytokine that controls the immune responses of B cells, T cells, and natural killer cells… 
Highly Cited
2017
Highly Cited
2017
Guiding immune cells to the center Germinal centers (GCs) are the site of antibody affinity maturation. The GC response… 
2017
2017
Bone marrow monocytes are primarily committed to osteoclast formation. It is, however, unknown whether potential primary… 
2014
2014
Systemic lupus erythematosus (SLE) is an autoimmune disease in which abnormal immune responses are mediated by tissue‐binding… 
2014
2014
ABSTRACT Interleukin-21 (IL-21) can be produced by CD8 T cells from HIV-1-infected individuals and those with autoimmune disease… 
2013
2013
Function exhaustion of specific cytotoxic CD8+ T cell in chronic virus infection partly results from the low levels of CD4 help… 
Highly Cited
2012
Highly Cited
2012
Interleukin (IL)‐21‐producing CD4+T cells are central to humoral immunity. Deciphering the signals that induce IL‐21 production… 
Highly Cited
2012
Highly Cited
2012
Female mice lacking DEF6 and SWAP70 develop a lupus-like syndrome through dysregulation of IRF4 in activated B cells and plasma… 
Highly Cited
2010
Highly Cited
2010
Previous studies have shown that IL‐6 potently induces IL‐21 production in CD4+ T cells, whereas TGF‐β inhibits IL‐6‐induced IL…