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interleukin-18 receptor activity

Known as: IL-18 receptor activity, IL-18R 
Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:jl… (More)

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Topic mentions per year

1998-2018
051019982018

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interleukin-18 binding activity

Related mentions per year

Related mentions per year

1997-2018
1990200020102020
interleukin-18 receptor activity
interleukin-18 binding activity

Papers overview

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2014
2014
Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction.
Acute myocardial infarction (AMI) is accompanied by increased expression of Toll like receptors (TLR)-2 and TLR4 on circulating… (More)
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2011
2011
Contributions of the MyD88-Dependent Receptors IL-18R, IL-1R, and TLR9 to Host Defenses following Pulmonary Challenge with Cryptococcus neoformans
Signaling via the adapter protein, MyD88, is important in the host defense against Cryptococcus neoformans infection. While… (More)
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2007
2007
Glial Expression of Interleukin-18 and its Receptor After Excitotoxic Damage in the Mouse Hippocampus
Interleukin (IL)-18, a member of the IL-1 cytokine family, is an important mediator of peripheral inflammation and host defence… (More)
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2007
2007
Variola virus IL-18 binding protein interacts with three human IL-18 residues that are part of a binding site for human IL-18 receptor alpha subunit.
Interleukin-18 (IL-18) plays an important role in host defense against microbial pathogens. Many poxviruses encode homologous IL… (More)
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2003
2003
Human dendritic cells express the IL-18R and are chemoattracted to IL-18.
IL-18 is secreted by a variety of cells such as epithelial cells, macrophages, and dendritic cells (DC), in particular, in areas… (More)
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2001
2001
Functional reconstitution and regulation of IL-18 activity by the IL-18R beta chain.
IL-18 and IL-12 are major IFN-gamma-inducing cytokines but the unique synergism of IL-18 and IL-12 remains unclear. In the human… (More)
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Highly Cited
2000
Highly Cited
2000
IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.
IL-18 is a proinflammatory cytokine that plays an important role in NK cell activation and T(h)1 response. IL-18 has a structural… (More)
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2000
2000
Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines
Interleukin-18 (IL-18) is a new inflammatory cytokine sharing biological functions with IL-12. The human IL-18 receptor (IL-18R… (More)
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Highly Cited
1998
Highly Cited
1998
Selective Expression and Functions of Interleukin 18 Receptor on T Helper (Th) Type 1 but not Th2 Cells
Interleukin (IL)-18 induces interferon (IFN)-gamma synthesis and synergizes with IL-12 in T helper type 1 (Th1) but not Th2 cell… (More)
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Highly Cited
1998
Highly Cited
1998
Differential capacities of CD4+, CD8+, and CD4-CD8- T cell subsets to express IL-18 receptor and produce IFN-gamma in response to IL-18.
IL-12 and IL-18 have the capacity to stimulate IFN-gamma production by T cells. Using a T cell clone, we reported that IL-18… (More)
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