interleukin-12 receptor

Known as: Receptors, IL-12, Receptor, Interleukin 12, IL-12 Receptors 
Cell surface receptors for INTERLEUKIN-12. They exist as dimers of beta 1 and beta 2 subunits. Signaling from interleukin-12 receptors occurs through… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0204019922018

Papers overview

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Highly Cited
2012
Highly Cited
2012
Foxp3(+) regulatory T (Treg) cells limit inflammatory responses and maintain immune homeostasis. Although comprised of several… (More)
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Highly Cited
2003
Highly Cited
2003
IL-12 promotes the proliferation of T cells as well as NK cells and plays a critical role in induction of the Th1 differentiation… (More)
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Highly Cited
1998
Highly Cited
1998
Interleukin-12 (IL-12) is a cytokine that promotes cell-mediated immunity to intracellular pathogens by inducing type 1 helper T… (More)
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Highly Cited
1997
Highly Cited
1997
Interleukin-12 (IL-12), a heterodimeric cytokine produced by activated monocytes and dendritic cells, plays a crucial role in… (More)
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Highly Cited
1997
Highly Cited
1997
The developmental commitment to a T helper 1 (Th1)- or Th2-type response can significantly influence host immunity to pathogens… (More)
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Highly Cited
1997
Highly Cited
1997
Two chains of the IL-12R, IL-12Rbeta1 and IL-12Rbeta2, have recently been cloned. To determine the role of IL-12Rbeta1 in… (More)
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Highly Cited
1996
Highly Cited
1996
We have identified a cDNA from a human phytohemagglutinin-activated lymphoblast library encoding a protein that binds 125I… (More)
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Highly Cited
1995
Highly Cited
1995
Interleukin-12 (IL-12) is a cytokine that has regulatory effects on T and natural killer (NK) cells and is composed of two… (More)
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Highly Cited
1994
Highly Cited
1994
Interleukin 12 (IL-12) facilitates the generation of a T helper type 1 (Th1) response, with high interferon gamma (IFN-gamma… (More)
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Highly Cited
1992
Highly Cited
1992
IL-12 is a heterodimeric lymphokine that induces IFN-gamma production by resting PBMC, enhances the lytic activity of NK… (More)
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