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insulin secretion

The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
MicroRNAs (miRNAs) constitute a growing class of non-coding RNAs that are thought to regulate gene expression by translational… Expand
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Highly Cited
2003
Highly Cited
2003
Diabetes, a disease in which carbohydrate and lipid metabolism are regulated improperly by insulin, is a serious worldwide health… Expand
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Review
2000
Review
2000
Glucose stimulates insulin secretion by generating triggering and amplifying signals in beta-cells. The triggering pathway is… Expand
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Highly Cited
1999
Highly Cited
1999
The pathogenesis of type 2 diabetes involves abnormalities in insulin action, insulin secretion, and endogenous glucose output… Expand
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Highly Cited
1995
Highly Cited
1995
Sulfonylureas are a class of drugs widely used to promote insulin secretion in the treatment of non-insulin-dependent diabetes… Expand
Highly Cited
1992
Highly Cited
1992
Insulin secretion rates can be accurately estimated from plasma C-peptide levels with a two-compartment model for C-peptide… Expand
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Highly Cited
1990
Highly Cited
1990
Two cell lines have been established from insulinomas obtained by targeted expression of the simian virus 40 T antigen gene in… Expand
Highly Cited
1988
Highly Cited
1988
The pattern of endogenous insulin secretion over a 24-h period, which included three mixed meals, was evaluated in 14 normal… Expand
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Highly Cited
1973
Highly Cited
1973
ABSTRACT The effect of very highly purified gastric inhibitory polypeptide (GIP) on insulin secretion in man was tested in normal… Expand
Highly Cited
1966
Highly Cited
1966
In previous studies we have demonstrated that in healthy subjects the ingestion of protein meals results in large increases in… Expand
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