insulin receptor binding

INTRODUCTION Imprinted genes play an important role in mammalian fetoplacental growth and development. We have evaluated whether… Expand

BACKGROUND Feeding a high-fructose diet induces hypertension and insulin-resistance in Sprague-Dawley rats. METHODS To… Expand

We have previously shown that a minimized insulin receptor (IR) consisting of the first 468 amino acids of the insulin receptor… Expand

Biological actions of insulin regulate glucose metabolism and other essential physiological functions. Binding of insulin to its… Expand

Increased insulinemic response to an oral glucose load has been demonstrated in Dahl salt-sensitive hypertensive rats. To… Expand

Chimeric receptors were generated in which structurally defined subdomains of the insulin receptor (IR) and insulin growth factor… Expand

We determined whether the palmitate effects on hepatocyte insulin receptor binding and post-receptor trafficking were mediated by… Expand

Insulinopenic states in rodents are known to cause an increase in the number of hepatic insulin receptors. To determine if this… Expand

Our previous studies indicated that amino acid residues 240-250 in the cysteine-rich region of the human insulin receptor alpha… Expand

Insulin receptor beta-subunit autophosphorylation, the first event occurring after insulin binding, plays a crucial role in… Expand