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insulin receptor binding

Interacting selectively and non-covalently with the insulin receptor. [GOC:ai]
National Institutes of Health

Papers overview

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2015
2015
Placental expression of the insulin receptor binding protein GRB10: Relation to human fetoplacental growth and fetal gender.
INTRODUCTION Imprinted genes play an important role in mammalian fetoplacental growth and development. We have evaluated whether… Expand
Highly Cited
2003
Highly Cited
2003
Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension.
BACKGROUND Feeding a high-fructose diet induces hypertension and insulin-resistance in Sprague-Dawley rats. METHODS To… Expand
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2002
2002
Functional Reconstitution of Insulin Receptor Binding Site from Non-binding Receptor Fragments*
We have previously shown that a minimized insulin receptor (IR) consisting of the first 468 amino acids of the insulin receptor… Expand
2000
2000
Insulin receptor binding kinetics: modeling and simulation studies.
Biological actions of insulin regulate glucose metabolism and other essential physiological functions. Binding of insulin to its… Expand
Highly Cited
1993
Highly Cited
1993
Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants.
Chimeric receptors were generated in which structurally defined subdomains of the insulin receptor (IR) and insulin growth factor… Expand
1993
1993
Mechanism of free fatty acid effects on hepatocyte insulin receptor binding and processing.
We determined whether the palmitate effects on hepatocyte insulin receptor binding and post-receptor trafficking were mediated by… Expand
1992
1992
Effects of STZ-Induced Diabetes and Fasting on Insulin Receptor mRNA Expression and Insulin Receptor Gene Transcription in Rat Liver
Insulinopenic states in rodents are known to cause an increase in the number of hepatic insulin receptors. To determine if this… Expand
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1991
1991
Insulin resistance and hypoglycemia in a patient with systemic lupus erythematosus: description of antiinsulin receptor antibodies that enhance insulin binding and inhibit insulin action.
We studied a patient with systemic lupus erythematosus and type B insulin resistance, who progressed from extreme insulin… Expand
1989
1989
Mutation of the high cysteine region of the human insulin receptor alpha-subunit increases insulin receptor binding affinity and transmembrane signaling.
Our previous studies indicated that amino acid residues 240-250 in the cysteine-rich region of the human insulin receptor alpha… Expand
1986
1986
Oral contraceptives and insulin receptor binding in normal women and those with previous gestational diabetes.
The effect of a low-dose triphasic oral contraceptive (ethinyl estradiol and levonorgestrel) on glucose tolerance, plasma insulin… Expand
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