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insulin receptor binding

Interacting selectively and non-covalently with the insulin receptor. [GOC:ai]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0102019752017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Molecular evidence supporting the portal theory: a causative link between visceral adiposity and hepatic insulin resistance.
The mechanism by which increased central adiposity causes hepatic insulin resistance is unclear. The "portal hypothesis… (More)
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2003
2003
Cellular mechanisms of insulin resistance in rats with fructose-induced hypertension.
BACKGROUND Feeding a high-fructose diet induces hypertension and insulin-resistance in Sprague-Dawley rats. METHODS To… (More)
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2000
2000
Insulin receptor binding kinetics: modeling and simulation studies.
Biological actions of insulin regulate glucose metabolism and other essential physiological functions. Binding of insulin to its… (More)
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Highly Cited
1998
Highly Cited
1998
Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease
The search for the causes of neurodegenerative disorders is a major theme in brain research. Acquired disturbances of several… (More)
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Highly Cited
1993
Highly Cited
1993
GLUT 4 and insulin receptor binding and kinase activity in trained human muscle.
1. Physical training enhances sensitivity and responsiveness of insulin-mediated glucose uptake in human muscle. This study… (More)
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Highly Cited
1990
Highly Cited
1990
Localization of insulin receptor mRNA in rat brain by in situ hybridization.
Insulin receptor mRNA was demonstrated in rat brain slices by in situ hybridization with three 35S-oligonucleotide probes and… (More)
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1989
1989
Effect of exercise on insulin receptor binding and kinase activity in skeletal muscle.
Insulin action in skeletal muscle is markedly enhanced for several hours after an acute bout of exercise. The purpose of this… (More)
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Highly Cited
1987
Highly Cited
1987
Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry.
In order to identify likely sites of action in insulin in rat brain we have used the technique of in vitro autoradiography and… (More)
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Highly Cited
1983
Highly Cited
1983
Pulsatile insulin has greater hypoglycemic effect than continuous delivery.
The relative hypoglycemic effects of pulsatile versus steadily infused insulin have been examined in six normal subjects in whom… (More)
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Highly Cited
1982
Highly Cited
1982
Cortisol-induced insulin resistance in man: impaired suppression of glucose production and stimulation of glucose utilization due to a postreceptor detect of insulin action.
The present studies were undertaken to assess the mechanisms responsible for cortisol-induced insulin resistance in man. The… (More)
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