insulin catabolic process

Known as: insulin breakdown, insulin catabolism, insulin degradation 
The chemical reactions and pathways resulting in the breakdown of insulin. [GOC:TermGenie]

Topic mentions per year

Topic mentions per year

1954-2017
05101519542016

Papers overview

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2009
2009
Insulin-degrading enzyme (IDE) is the ubiquitously expressed major enzyme responsible for insulin degradation. Insulin-degrading… (More)
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2004
2004
Endoplasmic reticulum (ER) stress, which is caused by the accumulation of misfolded proteins in the ER, elicits an adaptive… (More)
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Highly Cited
2003
Highly Cited
2003
Two substrates of insulin-degrading enzyme (IDE), amyloid beta-protein (Abeta) and insulin, are critically important in the… (More)
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Highly Cited
2003
Highly Cited
2003
Two substrates of insulin-degrading enzyme (IDE), amyloid -protein (A ) and insulin, are critically important in the pathogenesis… (More)
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2003
2003
Insulin-degrading enzyme is responsible for initiating insulin degradation in cells, but little is known about the factors… (More)
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Highly Cited
2000
Highly Cited
2000
Genetic analysis of the diabetic GK rat has revealed several diabetes susceptibility loci. Congenic strains have been established… (More)
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1990
1990
To characterize the role of the endosome in the degradation of insulin in liver, we employed a cell-free system in which the… (More)
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1988
1988
The effect of age and of prolonged caloric restriction on glucose tolerance and insulin responsiveness has been studied in male… (More)
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1978
1978
Insulin interaction with four human breast cancer cell lines in tissue culture was studied with respect to specific binding to… (More)
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1975
1975
The binding and the velocity of degradation of 125I-insulin in the absence or presence of varying concentrations of native… (More)
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