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inositol 1,4,5-trisphosphate phosphatase activity

Known as: D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity, Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity, inositol polyphosphate-5-phosphatase activity 
Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5… 
National Institutes of Health

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inositol trisphosphate phosphatase activityinositol-1,4,5-trisphosphate 5-phosphatase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2
Lowe syndrome is an X-linked disease that is characterized by congenital cataracts, central hypotonia, intellectual disability… 
2014
2014
A novel OCRL1 mutation in a patient with the mild phenotype of Lowe syndrome.
Oculocerebrorenal syndrome of Lowe (OCRL, OMIM 309000), also known as Lowe syndrome, is a rare X-linked multisystem disorder… 
1997
1997
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor…
Grb2/Ash and Shc are the adapter proteins that link tyrosine-kinase receptors to Ras and make tyrosine-kinase functionally… 
Highly Cited
1996
Highly Cited
1996
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity.
The production, survival, and function of monocytes and macrophages is regulated by the macrophage colony-stimulating factor (M… 
1990
1990
Divalent cation regulation of phosphoinositide metabolism. Naturally occurring B lymphoblasts contain a Mg2(+)-regulated phosphatidylinositol-specific phospholipase C.
Highly Cited
1982
Highly Cited
1982
The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane.
Human erythrocyte ghosts exhibit an inositol trisphosphate phosphomonoesterase activity that rapidly converts inositol 1,4,5… 
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