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inositol 1,4,5-trisphosphate phosphatase activity
Known as:
D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase activity
, Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphatase activity
, inositol polyphosphate-5-phosphatase activity
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Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5…
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National Institutes of Health
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2 relations
inositol trisphosphate phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The 5-phosphatase OCRL in Lowe syndrome and Dent disease 2
M. Matteis
,
Leopoldo Staiano
,
F. Emma
,
O. Devuyst
Nature Reviews Nephrology
2017
Corpus ID: 20408143
Lowe syndrome is an X-linked disease that is characterized by congenital cataracts, central hypotonia, intellectual disability…
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2014
2014
A novel OCRL1 mutation in a patient with the mild phenotype of Lowe syndrome.
K. Sugimoto
,
Hitomi Nishi
,
T. Miyazawa
,
S. Fujita
,
M. Okada
,
T. Takemura
Tohoku journal of experimental medicine
2014
Corpus ID: 23553887
Oculocerebrorenal syndrome of Lowe (OCRL, OMIM 309000), also known as Lowe syndrome, is a rare X-linked multisystem disorder…
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1997
1997
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor…
H. Odai
,
K. Sasaki
,
+6 authors
H. Hirai
Blood
1997
Corpus ID: 6273335
Grb2/Ash and Shc are the adapter proteins that link tyrosine-kinase receptors to Ras and make tyrosine-kinase functionally…
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Highly Cited
1996
Highly Cited
1996
p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity.
M. Lioubin
,
P. Algate
,
S. Tsai
,
K. Carlberg
,
A. Aebersold
,
L. Rohrschneider
Genes & Development
1996
Corpus ID: 21109045
The production, survival, and function of monocytes and macrophages is regulated by the macrophage colony-stimulating factor (M…
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1990
1990
Divalent cation regulation of phosphoinositide metabolism. Naturally occurring B lymphoblasts contain a Mg2(+)-regulated phosphatidylinositol-specific phospholipase C.
M. M. Chien
,
J. Cambier
Journal of Biological Chemistry
1990
Corpus ID: 42976492
Highly Cited
1982
Highly Cited
1982
The inositol trisphosphate phosphomonoesterase of the human erythrocyte membrane.
C. Downes
,
M. Mussat
,
R. Michell
Biochemical Journal
1982
Corpus ID: 21945048
Human erythrocyte ghosts exhibit an inositol trisphosphate phosphomonoesterase activity that rapidly converts inositol 1,4,5…
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