inflammasome complex

Known as: inflammasome complex location 
A cytosolic protein complex that is capable of activating caspase-1. [GOC:dph, PMID:17599095]
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2017
0204020052017

Papers overview

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Highly Cited
2013
Highly Cited
2013
NLRP3 is an important pattern recognition receptor involved in mediating inflammasome activation in response to viral and… (More)
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2013
2013
The NLRP3 inflammasome plays a major role in innate immune responses by activating caspase-1, resulting in secretion of… (More)
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2012
2012
Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine involved in the pathogenesis of HCV, but the sensors and underlying… (More)
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Highly Cited
2012
Highly Cited
2012
Inflammasome is a multiprotein complex consisting of Nod-like receptor protein 3 (NALP3), apoptosis-associated speck-like protein… (More)
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2011
2011
Tubule-interstitial nephritis (TIN) results in decreased renal function and interstitial inflammation, which ultimately leads to… (More)
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Highly Cited
2010
Highly Cited
2010
IL-1beta produced by phagocytes is important for protection against the mucosal pathogen Staphylococcus aureus. Processing and… (More)
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Highly Cited
2009
Highly Cited
2009
The inflammasome is a multiprotein complex involved in innate immunity. Activation of the inflammasome causes the processing and… (More)
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2009
2009
Periodontitis is an infectious process characterized by inflammation affecting the supporting structures of the teeth… (More)
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2009
2009
Multiple microbial components trigger the formation of an inflammasome complex that contains pathogen-specific nucleotide… (More)
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Highly Cited
2007
Highly Cited
2007
The CATERPILLER (CLR/NLR) gene family encodes a family of putative nucleotide-binding proteins important for host defense… (More)
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