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indirubin-3'-monoxime

 
National Institutes of Health

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2014
2014
Recent studies have highlighted that diabetes mellitus (DM) is a strong risk factor for Alzheimer's disease (AD). Insulin… Expand
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2010
2010
Indirubin and its derivatives have been shown to possess potent inhibitory effects on cyclin-dependent protein kinase 5 and… Expand
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2010
2010
OBJECTIVE Our goal was to examine the influence of indirubin-3'-monoxime (I3MO), a natural product-derived cyclin-dependent… Expand
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2009
2009
Increasing evidence suggests that the inappropriate activation of cyclin-dependent kinases (CDKs) could induce neuronal apoptosis… Expand
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2008
2008
Notch proteins perform a critical function in cell-fate decisions and in differentiation. In this study, we determined that… Expand
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Highly Cited
2007
Highly Cited
2007
Pathologic angiogenesis has emerged as an important therapeutic target in several major diseases. Zebrafish offer the potential… Expand
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2006
2006
In traditional Chinese Medicine, the preparation Danggui Longhui Wan has been used for years in the treatment of chronic… Expand
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2005
2005
OBJECTIVE To evaluate the effects of the cyclin dependent kinase (CDK) inhibitor Indirubin-3'-monoxime (IM) on Tat-mediated… Expand
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Highly Cited
2003
Highly Cited
2003
We have previously examined the specificities of 28 commercially available compounds, reported to be relatively selective… Expand
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Highly Cited
2001
Highly Cited
2001
The bis-indole indirubin is an active ingredient of Danggui Longhui Wan, a traditional Chinese medicine recipe used in the… Expand
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