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immunophilin activity

Known as: immunophilin 
OBSOLETE. Any member of a family of receptors that includes the major FK506 binding protein FKBP and cyclophilin. These two proteins are unrelated in… 
National Institutes of Health

Related topics

Related topics

3 relations
ImmunophilinsPPIase activityPeptidylprolyl Isomerase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
A β-Turn Motif in the Steroid Hormone Receptor's Ligand-Binding Domains Interacts with the Peptidyl-prolyl Isomerase (PPIase) Catalytic Site of the Immunophilin FKBP52.
The immunophilin FKBP52 interacts with nuclear steroid hormone receptors. Studying the crystal structure of human estrogen… 
Review
2005
Review
2005
Neuroprotection in the PNS: erythropoietin and immunophilin ligands.
Many illnesses that affect the peripheral nervous system (PNS) lead to distal axonal degeneration rather than loss of neuronal… 
Highly Cited
2001
Highly Cited
2001
ortho‐Substituted PCB95 alters intracellular calcium signaling and causes cellular acidification in PC12 cells by an immunophilin‐dependent mechanism
ortho‐Substituted PCBs mobilize Ca2+ from isolated brain microsomes by interaction with FKBP12/RyR complexes. Investigation into… 
2001
2001
Sirolimus (rapamycin) in clinical transplantation
Review
1995
Review
1995
Receptor (Immunophilin‐Bhiding) Assay for Immunosuppressive Drugs
Summary The major immunophilins that bind cyclosporine (cyclophilin) and FK-506/rapamycin (FK-BP12) have been well characterized… 
1994
1994
FKBP46, a novel Sf9 insect cell nuclear immunophilin that forms a protein-kinase complex.
Review
1993
Review
1993
The hsp56 immunophilin component of steroid receptor heterocomplexes: Could this be the elusive nuclear localization signal-binding protein?
1993
1993
The mammalian heat shock protein binding immunophilin (p59/HBI) is an ATP and GTP binding protein.
A protein of M(r) 59,000 (p59) was recently cloned and identified as a Heat shock protein Binding Immunophilin (p59/HBI). It… 
1993
1993
Cloning and expression of a mouse cDNA encoding p59, an immunophilin that associates with the glucocorticoid receptor.
Highly Cited
1992
Highly Cited
1992
A rapamycin-selective 25-kDa immunophilin.
FKBP25, a previously uncharacterized 25-kDa FK506- and rapamycin-binding protein, was purified to homogeneity from calf thymus… 
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