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imidazopyrazole

Known as: 1H-imidazo(1,2-b)pyrazole 
 
National Institutes of Health

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3 relations

Narrower (2)

NSC 51143imidazolopyrazole

Broader (1)

Pyrazoles

Papers overview

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2020
2020
New Hybrid Pyrazole and Imidazopyrazole Antinflammatory Agents Able to Reduce ROS Production in Different Biological Targets
Several anti-inflammatory agents based on pyrazole and imidazopyrazole scaffolds and a large library of substituted catechol… Expand
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2020
2020
DISCOVERY OF NEW ANTIPROLIFERATIVE IMIDAZOPYRAZOLE ACYLHYDRAZONES ABLE TO INTERACT WITH MICROTUBULE SYSTEM.
Despite immunotherapy has radically changed the anticancer search, there are still many different pathways that are open to… Expand
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2017
2017
Design, synthesis and biological evaluation of new pyrazolyl-ureas and imidazopyrazolecarboxamides able to interfere with MAPK and PI3K upstream signaling involved in the angiogenesis.
Taking into account the structure activity relationship information given by our previous studies, we designed and synthesized a… Expand
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2016
2016
An Eco-Friendly Synthesis of Heterocyclic Moieties Condensed with Pyrazole System under Green Conditions and Their Biological Activity
The efficient, facile and green synthesis of 4-bromo pyrazolone by using N-bromo saccharine as valuable green reagent encouraged… Expand
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2014
2014
Abstract 1026: Novel Tie2 inhibitor with in vivo efficacy in disseminated hematological tumor models in mice
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA The receptor tyrosine kinase Tie2 is predominantly… Expand
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Highly Cited
2011
Highly Cited
2011
N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIα and induce apoptosis in G1/S phase.
On the basis of structures of known topoisomerase II catalytic inhibitors and initial molecular docking studies, bicyclic N-fused… Expand
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2006
2006
Transport and Metabolism of Deoxycytidine and 1-ß-D-Arabinofuranosyl-cytosine into Cultured Novikoff Rat Hepatoma Cells , Relationship to Phosphorylation , and Regulation of Triphosphate Synthesis 1
The zero-trans transport of deoxycytidine and 1-/3-Darabinofuranosylcytosine was determined in cultured No vikoff rat hepatoma… Expand
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1993
1993
Prepn. of imidazopyrazole derivatives as analgesics and anti-inflammatory agents
The compounds of formula (I) shown below and a preparation method thereof can be applied in pharmaceutically acceptable salt… Expand
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1982
1982
GC analysis of imidazopyrazole in plasma using nitrogen-specific detection.
A sensitive, specific GC assay for imidazopyrazole in plasma was developed using nitrogen-specific detection. The samples are… Expand
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1980
1980
Studies on the clinical pharmacokinetics of imidazopyrazole.
Plasma decay kinetics were analyzed for seven patients (400-5700 mg) during a Phase I clinical trial of imidazopyrazole. A two… Expand
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