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imidazole mustard

Known as: BIC mustard, 5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide, HN2 
A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BackgroundPartitioning involves estimating independent models of molecular evolution for different subsets of sites in a sequence… Expand
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Highly Cited
2005
Highly Cited
2005
We show that the microRNA miR-155 can be processed from sequences present in BIC RNA, a spliced and polyadenylated but non… Expand
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Highly Cited
2005
Highly Cited
2005
In a previous study we demonstrated high expression of the non-coding BIC gene in the vast majority of Hodgkin's lymphomas (HLs… Expand
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Highly Cited
2004
Highly Cited
2004
Pseudomonas aeruginosa is the predominant cause of chronic airway infection in cystic fibrosis (CF). CF airway isolates are often… Expand
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Highly Cited
2001
Highly Cited
2001
This paper develops consistent model and moment selection criteria for GMM estimation. The criteria select the correct model… Expand
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Highly Cited
2000
Highly Cited
2000
The mechanisms by which DNA interstrand cross-links (ICLs) are repaired in mammalian cells are unclear. Studies in bacteria and… Expand
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Highly Cited
1997
Highly Cited
1997
In the problem of selecting a linear model to approximate the true un- known regression model, some necessary and/or sufficient… Expand
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Highly Cited
1994
Highly Cited
1994
A new criterion is proposed for the evaluation of variable selection procedures in multiple regression. This criterion, which we… Expand
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Highly Cited
1960
Highly Cited
1960
Abstract Suggestions are made for the conduct of chemotherapy trials in patients with cancer. Application of the principles… Expand
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Highly Cited
1952
Highly Cited
1952
Introduction and Aim: Endotracheal intubation (EI) is vital in emergency medicine where airway management is critical. In… Expand
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