imidazole-4-carboxamide
National Institutes of Health
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A series of poly(ADP-ribose)polymerase (PARP)-1 inhibitors containing a novel scaffold, the 1H-thieno[3,4-d]imidazole-4…
Oligodeoxyribonucleotides containing the nucleoside analog 1-(2'-deoxy-beta-D-ribofuranosyl) imidazole-4-carboxamide (1) were…
The treatment of mice bearing i.m. B16 melanoma with equitoxic dosages of the clinically used 5-(3,3-dimethyl-1-triazeno…
The anti-tumour methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide (MTIC) increased the thymidine and…
Immunologic alteration of the L5178Y lymphoma was obtained in vivo after treatment with 5-(3,3-dimethyl-1-triazeno)imidazole-4…
Excerpt We have observed a dramatic response of melanoma with disseminated intravascular coagulation to a chemotherapeutic agent…
Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno), NSC 45388 (DTIC), was administered for 5 consecutive days as a rapid 150-mg…
Courses of treatment with a combination of 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide (NSC-45388) (850 mg/m2…