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imetit

Known as: Carbamimidothioic acid, 2-(1H-imidazol-4-yl)ethyl ester, S-(2-(4-imidazolyl)ethyl)isothiourea 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the… Expand
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Highly Cited
2004
Highly Cited
2004
During mast cell degranulation, histamine is released in large quantities. Human eosinophils were found to express histamine H4… Expand
Highly Cited
2004
Highly Cited
2004
The role of histamine H1, H2, H3 and H4 receptors in acute itch induced by histamine was investigated in female BalbC mice… Expand
Highly Cited
2003
Highly Cited
2003
Histamine (0.004–2 μM) induced a concentration‐dependent shape change of human eosinophils, but not of neutrophils or basophils… Expand
Review
2001
Review
2001
Using a genomics-based reverse pharmacological approach for screening orphan G-protein coupled receptors, we have identified and… Expand
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Highly Cited
2000
Highly Cited
2000
A new histamine receptor, HH4R, was cloned from human leukocyte cDNA. The deduced amino acid sequence showed about 40% identity… Expand
Highly Cited
1996
Highly Cited
1996
1 The effects of histamine and agents acting at histamine receptors on spontaneous and 100 mM K+‐evoked release of acetylcholine… Expand
Highly Cited
1996
Highly Cited
1996
All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the… Expand
Highly Cited
1995
Highly Cited
1995
1 The pharmacological properties and location of H3 receptors modulating acetylcholine release have been investigated in non… Expand
Review
1994
Review
1994
Summary— Presynaptic H3 receptors occur on histaminergic neurones of the CNS (autoreceptors) and on non‐histaminergic neurones of… Expand