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Brain histaminergic neurons play a prominent role in arousal and maintenance of wakefulness (W). H(3)-receptors control the… Expand During mast cell degranulation, histamine is released in large quantities. Human eosinophils were found to express histamine H4… Expand The role of histamine H1, H2, H3 and H4 receptors in acute itch induced by histamine was investigated in female BalbC mice… Expand Histamine (0.004–2 μM) induced a concentration‐dependent shape change of human eosinophils, but not of neutrophils or basophils… Expand Using a genomics-based reverse pharmacological approach for screening orphan G-protein coupled receptors, we have identified and… Expand A new histamine receptor, HH4R, was cloned from human leukocyte cDNA. The deduced amino acid sequence showed about 40% identity… Expand 1 The effects of histamine and agents acting at histamine receptors on spontaneous and 100 mM K+‐evoked release of acetylcholine… Expand All previously reported CAAX-based farnesyltransferase inhibitors contain a thiol functionality. We report that attachment of the… Expand 1 The pharmacological properties and location of H3 receptors modulating acetylcholine release have been investigated in non… Expand Summary— Presynaptic H3 receptors occur on histaminergic neurones of the CNS (autoreceptors) and on non‐histaminergic neurones of… Expand