ilomastat

Known as: Butanediamide, N4-hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-,(2R)-, N'-hydroxy-N-((S)-2-indol-3-yl-1-(methylcarbamoyl)ethyl)-2-isobutylsuccinamide, N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan Methylamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2016
012319992016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Novel Ilomastat analogs with substituted benzamide groups, instead of hydroxamic acid groups, were designed, synthesized and… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2014
2014
Pharmacological inhibition of matrix metalloproteinase-2 (MMP-2) is a promising target for acute cardioprotection against… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2012
2012
We are developing tablet dosage forms for implantation directly into the subconjunctival space of the eye. The matrix… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
BACKGROUND An increase in matrix metalloproteinases (MMPs) and the resulting degradation of the extracellular matrix have been… (More)
Is this relevant?
2005
2005
PURPOSE To determine the long-term antiscarring effect of ilomastat treatment after experimental glaucoma filtration surgery (GFS… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2005
2005
Lethal toxin, produced by the bacterium Bacillus anthracis, is a major contributor to morbidity and mortality in animals and… (More)
Is this relevant?
2005
2005
Activated microglia contribute to cell death in ischemic and neurodegenerative disorders of the CNS. Microglial activation is… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
2003
2003
OBJECTIVES Proteases of both the serine and metalloproteinase families have been shown to play a role in the pathogenesis of… (More)
Is this relevant?
2003
2003
PURPOSE To determine whether postoperative application of a broad-spectrum matrix metalloproteinase (MMP) inhibitor, GM6001… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2002
2002
When mouse 3T3-L1 preadipocytes are induced to differentiate into adipocytes, they change from an extended fibroblast-like… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?