icotinib

Known as: 4-((3-ethynylphenyl)amino)-6,7-benzo-12-crown-4-quinazoline 
 
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND For patients with non-small-cell lung cancer (NSCLC) and multiple brain metastases, whole-brain irradiation (WBI) is a… (More)
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Review
2015
Review
2015
According to Chinese Cancer Registry Annual Report in 2011, the incidence rate of lung cancer was 48.32/100,000 and the mortality… (More)
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2015
2015
Lung cancer has the highest mortality rate of all cancers worldwide. A total of 70%-75% of all lung cancers are non-small cell… (More)
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2015
2015
BACKGROUND Epidermal growth factor receptor (EGFR) mutations occur in up to 50% of Asian patients with non-small cell lung cancer… (More)
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2014
2014
BACKGROUND Several EGFR-tyrosine kinase inhibitors (EGFR-TKIs) including erlotinib, gefitinib, afatinib and icotinib are… (More)
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2014
2014
ABCG2 is a potential biomarker causing multidrug resistance (MDR) in Non-Small Cell Lung Cancer (NSCLC). We conducted this study… (More)
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2014
2014
BACKGROUND The phase 3 ICOGEN trial established the non-inferiority of icotinib to gefitinib in terms of progression-free… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Icotinib, an oral EGFR tyrosine kinase inhibitor, had shown antitumour activity and favourable toxicity in early-phase… (More)
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2013
2013
Icotinib is a potent and specific epidermal growth factor receptor tyrosine kinase inhibitor. In this study, we reported that… (More)
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Highly Cited
2012
Highly Cited
2012
Icotinib, one of the leading compounds selected from our compound library, was found to be a potent and specific epidermal growth… (More)
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