ibutilide fumarate

Known as: (+-)-4'-(4-(Ethylheptylamino)-1-hydroxybutyl)methanesulfonanilide Fumarate(2:1)(salt) 
The fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium… (More)

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1991-2010
02419912010

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2010
2010
BACKGROUND Ibutilide is a class III antiarrhythmic drug, frequently used for conversion of atrial fibrillation and flutter… (More)
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2006
2006
BACKGROUND Ibutilide is a class III antiarrhythmic drug, frequently used for conversion of atrial fibrillation and flutter. We… (More)
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1999
1999
BACKGROUND Atrial arrhythmias occur commonly after cardiac surgery and are a cause of significant morbidity and increased… (More)
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1998
1998
OBJECTIVES This multicenter study compared the efficacy and safety of ibutilide versus procainamide for conversion of recent… (More)
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1998
1998
BACKGROUND A study was conducted to determine the efficacy and safety of ibutilide fumarate versus placebo in the acute… (More)
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1996
1996
OBJECTIVES Currently available antiarrhythmic drugs have limited efficacy for short-term, rapid termination of atrial… (More)
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1996
1996
In two Segment II Teratology studies, timed-pregnant Crl:CD[BR] (Sprague-Dawley) rats were treated orally (gastric intubation) on… (More)
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1996
1996
INTRODUCTION Atrial arrhythmias are a frequent clinical complication following open heart surgery. We compared the Class III… (More)
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1994
1994
Polymer-drug composites known as controlled-release systems have been used effectively to prevent and treat ventricular… (More)
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1992
1992
Ibutilide fumarate is currently in Phase II clinical trials for the treatment of life-threatening cardiac arrhythmias. The… (More)
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