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ibodutant

Known as: benzo(b)thiophene-2-carboxamide, 6-methyl-N-(1-((((1R)-2- oxo-1-(phenylmethyl)-2-(((1-((tetrahydro-2H-pyran-4- yl)methyl)-4- piperidinyl)methyl)amino)ethyl)amino)carbonyl)cyclopentyl)- 
 
National Institutes of Health

Papers overview

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2017
2017
Background Tachykinins have been implicated in the pathophysiology of IBS with diarrhoea (IBS-D). Our aim was to study the… Expand
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2016
2016
BACKGROUND AND PURPOSE The tachykinin NK2 receptor antagonist ibodutant is under Phase III clinical investigation to treat female… Expand
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2013
2013
We have characterized the pharmacological profile of the nonpeptide tachykinin NK2 receptor antagonist ibodutant (MEN15596… Expand
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2013
2013
In this study we have characterized the pharmacological profile of the non-peptide tachykinin NK2 receptor antagonist ibodutant… Expand
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2013
2013
We recently identified hexamethonium-resistant peristalsis in the guinea pig colon. We showed that, following acute blockade of… Expand
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2013
2013
In this study we have characterized the pharmacological profile of the non-peptide tachykinin NK(2) receptor antagonist ibodutant… Expand
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2011
2011
BACKGROUND The present aim was to study the modulation of NK2 receptor internalization by two compounds, the spasmolytic… Expand
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2009
2009
Ibodutant (MEN15596, [1-(2-phenyl-1R-[[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl]-ethylcarbamoyl… Expand
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1992
1992
Investigation of the SAR of the lead (methoxyalkyl)thiazole 1-[3-(naphth-2-ylmethoxy)phenyl]-1-thiazol-2-ylprop yl methyl ether… Expand
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