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ibodutant

Known as: benzo(b)thiophene-2-carboxamide, 6-methyl-N-(1-((((1R)-2- oxo-1-(phenylmethyl)-2-(((1-((tetrahydro-2H-pyran-4- yl)methyl)-4- piperidinyl)methyl)amino)ethyl)amino)carbonyl)cyclopentyl)- 
National Institutes of Health

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2 relations

Broader (2)

DipeptidesThiophenes

Papers overview

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2015
2015
Mo2041 Effect of Ibodutant, a Neurokinin NK2 Receptor Antagonist, on Gender-Related Influences Following Induction of Trinitrobenzenesulfonic Acid-Induced Colitis in the Guinea Pig
2014
2014
Thermal and optical properties of 4H-pyran-4-ylidene fragment and bis-styryl and triphenyl groups containing derivatives
Small D-π-A type organic molecules with incorporated 4H-pyan-4-ylidene (pyranylidene) fragment in their structures show potential… 
2014
2014
Sa1080 Concordance Among Outcome Variables Assessing the Response to Treatment With Ibodutant in Irritable Bowel Syndrome With Diarrhea (IBS-D; the IRIS-2 Study)
2013
2013
Peristalsis and propulsion of colonic content can occur after blockade of major neuroneuronal and neuromuscular transmitters in isolated guinea pig colon.
We recently identified hexamethonium-resistant peristalsis in the guinea pig colon. We showed that, following acute blockade of… 
2013
2013
Antagonist profile of ibodutant at the tachykinin NK(2) receptor in guinea pig isolated bronchi.
In this study we have characterized the pharmacological profile of the non-peptide tachykinin NK(2) receptor antagonist ibodutant… 
2011
2011
Effect of otilonium bromide and ibodutant on the internalization of the NK2 receptor in human colon
Background  The present aim was to study the modulation of NK2 receptor internalization by two compounds, the spasmolytic… 
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