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ibodutant

Known as: benzo(b)thiophene-2-carboxamide, 6-methyl-N-(1-((((1R)-2- oxo-1-(phenylmethyl)-2-(((1-((tetrahydro-2H-pyran-4- yl)methyl)-4- piperidinyl)methyl)amino)ethyl)amino)carbonyl)cyclopentyl)- 
 
National Institutes of Health

Papers overview

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2016
2016
Background Tachykinins have been implicated in the pathophysiology of IBS with diarrhoea (IBS-D). Our aim was to study the… Expand
2016
2016
The tachykinin NK2 receptor antagonist ibodutant is under Phase III clinical investigation to treat female patients with… Expand
2013
2013
We have characterized the pharmacological profile of the nonpeptide tachykinin NK2 receptor antagonist ibodutant (MEN15596… Expand
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2013
2013
In this study we have characterized the pharmacological profile of the non-peptide tachykinin NK2 receptor antagonist ibodutant… Expand
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2013
2013
We recently identified hexamethonium-resistant peristalsis in the guinea pig colon. We showed that, following acute blockade of… Expand
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2013
2013
In this study we have characterized the pharmacological profile of the non-peptide tachykinin NK(2) receptor antagonist ibodutant… Expand
2011
2011
Background  The present aim was to study the modulation of NK2 receptor internalization by two compounds, the spasmolytic… Expand
2009
2009
Ibodutant (MEN15596, [1-(2-phenyl-1R-{[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl}-ethylcarbamoyl… Expand
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Highly Cited
1992
Highly Cited
1992
Investigation of the SAR of the lead (methoxyalkyl)thiazole 1-[3-(naphth-2-ylmethoxy)phenyl]-1-thiazol-2-ylprop yl methyl ether… Expand