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hypoxanthine phosphoribosyltransferase activity
Known as:
inosine 5'-phosphate pyrophosphorylase activity
, IMP pyrophosphorylase activity
, IMP-GMP pyrophosphorylase activity
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Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. [EC:2.4.2.8, GOC:curators]
National Institutes of Health
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Related topics
Related topics
3 relations
Adenine Phosphoribosyltransferase
HPRT1 gene
Hypoxanthine Phosphoribosyltransferase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
32. The expression of ovulatory mediators by macrophages isolated from the gonadotrophin-stimulated mouse ovary
K. H. V. Hoek
,
N. Ryan
,
S. Robertson
,
R. Norman
2003
Corpus ID: 84245180
IL-1beta (IL-1β), TNF alpha (TNFα), nitric oxide (NO) and macrophages have been shown to be important in stimulating the…
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2002
2002
Restoration ofHypoxanthine Phosphoribosyl Transferase Activity inMouse1R Cells AfterFusionwithChick-Embryo Fibroblasts (mouse-chick clones/enzyme activation/regulator gene)
B. Bakay
,
Carlo M. Crocet
,
Hilary Koprowskit
2002
Corpus ID: 10141096
FusionoftheIRmousecell, whichlacks activityof hypoxanthine phosphoribosyl transferase (EC2.4.2.8), withchick-embryo fibroblasts…
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1997
1997
Partial Male Sterility in Transgenic Tobacco Plants Carrying Small Subunit ADPglucose Pyrophosphorylase cDNAs from Sweet Potato
J. Bae
,
C. Harn
,
Kwoung H. Tae
,
Jang-R. Liu
1997
Corpus ID: 86123998
1980
1980
Guanosine metabolism in Neurospora crassa.
W. Greer
,
L. Pendyala
,
A. Wellman
Canadian Journal of Biochemistry
1980
Corpus ID: 39964145
Two aspects of guanosine metabolism in Neurospora have been investigated. (a) The inability of adenine mutants (blocked prior to…
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1980
1980
Subcellular distribution of PRibPP synthetase activity of rat intestinal mucosa.
L. Yip
,
A. K. Yeh
,
M. Baliś
American Journal of Physiology
1980
Corpus ID: 25025902
5-Phosphoribosyl 1-pyrophosphate synthetase (PRibPP synthetase EC 2.7.6.1) isolated from rat intestinal mucosa was found to be…
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Highly Cited
1977
Highly Cited
1977
Assignment of the genes for thymidine kinase and galactokinase toMus musculus chromosome 11 and the preferential segregation of this chromosome in Chinese hamster/mouse somatic cell hybrids
C. Kozak
,
F. Ruddle
Somatic Cell Genetics
1977
Corpus ID: 42426048
Somatic cell genetic techniques were used to establish linkage assignments for the loci coding for galactokinase (GLK) and…
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Highly Cited
1976
Highly Cited
1976
Monoamine oxidase activity decreased in cells lacking hypoxanthine phosphoribosyltransferase activity.
X. Breakefield
,
C. Castiglione
,
S. B. Edelstein
Science
1976
Corpus ID: 44532918
The Lesch-Nyhan syndrome in humans is characterized by lack of hypoxanthine phosphoribosyltransferase activity and neurologic…
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1972
1972
Absence of Metabolic Co-Operation between Certain Types of Mammalian Cells in Culture
Chantal Widmer-Favre
1972
Corpus ID: 85634657
A mutant line of BHK 21 cells lacking inosinic pyrophosphorylase activity (IPP - cells) does not incorporate [ 3 H]hypoxanthine…
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1969
1969
Hybridization of two biochemically marked human cell lines.
S. Silagi
,
G. Darlington
,
S. A. Bruce
Proceedings of the National Academy of Sciences…
1969
Corpus ID: 7346398
A hybrid cell line of clonal origin has been obtained by cocultivation of two biochemically marked human cell strains. One…
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