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hypermethylation of CpG island
Known as:
DNA hypermethylation of CpG island
An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a…
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National Institutes of Health
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Papers overview
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Review
2011
Review
2011
DIRAS3 (DIRAS family, GTP -binding RAS -like 3)
Yin-hua Yu
,
Zhen Lu
,
Robert Z. Luo
,
R. Bast
2011
Corpus ID: 85149288
Review on DIRAS3 (DIRAS family, GTP-binding RAS-like 3), with data on DNA, on the protein encoded, and where the gene is…
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2011
2011
Aberrant CpG Island Hypermethylation and Down-Regulation of Oct-6 mRNA Expression in Human Hepatocellular Carcinoma
Jing-zhe Sun
,
Xuexi Yang
,
+4 authors
Ming Li
Digestive Diseases and Sciences
2011
Corpus ID: 24076048
BackgroundAberrant CpG island hypermethylation is a major epigenetic mechanism that can inactivate the transcription of cancer…
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2009
2009
在肿瘤、非肿瘤的胃的 epithelia 的肿瘤 suppressor 和肿瘤相关的基因的 Hypermethylation
Tamura
2009
Corpus ID: 89586028
A number of tumor suppressor and tumor-related genes exhibit promoter hypermethylation with resultant gene silencing in human…
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2008
2008
Nucleosome Positions and Differential Methylation Status of Various Regions within MLH1 CpG Island
白桦
,
周静
,
邓大君
2008
Corpus ID: 92041202
目的将在 MLH1 CpG 岛以内决定在 nucleosome 位置和报导区域 A， B， C，和 D 的微分甲基化的形成之间的关系。MLH1 倡导者的方法甲基化被分析由重亚硫酸盐联合了限制试金。RKO 和 MGC803 房间的染色质被 MNase…
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2006
2006
Human Cancers Associated with Aberrant DNA Methylation in All Common Gene Is Frequently CDKN 2 / p 16 / MTS 1 Inactivation of the Updated
J. Herman
,
A. Merlo
,
+5 authors
S. Baylin
2006
Corpus ID: 17520572
The tumor suppressor gene CDKN2/p16/MTSI,located on chromosome 9p21, is frequenfly inactivated in many human cancers through…
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2005
2005
Epigenetic Mechanisms of Gene Regulation: Relationships between DNA Methylation, Histone Modification, and Chromatin Structure
K. Robertson
2005
Corpus ID: 38092536
DNA methylation is a post-replicative, or epigenetic, modification of the genome that is critical for proper mammalian embryonic…
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2004
2004
Preferential Tyrosine Phosphorylation ofMutant ERK2 (E322K) and Upregulation ofInterferon Induced Genes in OSCC cell lineHSC6
Ramanathan Arvind
,
松村 耕治
,
金田 善正
,
小村 健
2004
Corpus ID: 228641812
2004
2004
The hypermethylation of CpG island in promoter regions and protein expression of O~6-methylguanine-DNA methyltransferase gene in colorectal tumor
Z. You
2004
Corpus ID: 86925215
Objective To investigate the effect of promoter hypermethylation of O 6 methylguanine DNA methyltransferase (MGMT) gene on…
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2002
2002
Hypermethylation of HPP 1 Is Associated with hMLH 1 Hypermethylation in Gastric Adenocarcinomas 1
D. Shibata
,
F. Sato
,
+10 authors
S. Meltzer
2002
Corpus ID: 36228860
The HPP1 gene was initially discovered because of its frequent hypermethylation in hyperplastic colon polyps, but it is also…
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2001
2001
Isolation and Characterization of the Murine Homeobox Gene Cdx-1 REGULATION OF EXPRESSION IN INTESTINAL EPITHELIAL CELLS
Yinling HuS
,
Jan KazenwadelSQ
,
Robert JamesSQll
2001
Corpus ID: 51123006
The murine homeobox gene Cdx-1 is postulated to play an important role in the process of cellular commitment in the intestinal…
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