FAQ

hydroxytamoxifen

 

Topic mentions per year

Topic mentions per year

1980-2017
051019802017

Related topics

Related topics

1 relation

Broader (1)

Tamoxifen

Related mentions per year

Related mentions per year

1955-2018
1960198020002020
hydroxytamoxifen
Tamoxifen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF.
The steroid hormone oestrogen can signal through several receptors and pathways. Although the transcriptional responses mediated… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells.
The growth of both normal and transformed epithelial cells of the female reproductive system is stimulated by estrogens, mainly… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2005
2005
Neoadjuvant percutaneous 4-hydroxytamoxifen decreases breast tumoral cell proliferation: a prospective controlled randomized study comparing three doses of 4-hydroxytamoxifen gel to oral tamoxifen.
PURPOSE Two chemoprevention randomized studies using tamoxifen showed drug efficacy; however, adverse effects such as hot flushes… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.
Nuclear receptors (NRs) bound to response elements mediate the effects of cognate ligands on gene expression. Their ligand… (More)
Is this relevant?
1994
1994
Tamoxifen and hydroxytamoxifen as intramembraneous inhibitors of lipid peroxidation. Evidence for peroxyl radical scavenging activity.
Tamoxifen (TAM) is the antiestrogen most widely used in the chemotherapy and chemoprevention of breast cancer. It has been… (More)
Is this relevant?
1993
1993
Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen.
We have generated mutant mouse estrogen receptors which differ in their sensitivity to estrogen and the antiestrogen 4… (More)
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer.
Extracts containing wild-type or mutant human estrogen receptor (ER) have been used to study the binding of ER to its responsive… (More)
Is this relevant?
1988
1988
Tamoxifen and hydroxytamoxifen isomers versus estradiol effects on normal human breast cells in culture.
Estradiol and triphenylethylene antiestrogen actions have been studied extensively in breast cancer cell lines. However, their… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Although much attention has been paid to the removal of hormones from sera and to the development of serum-free media for studies… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
Tamoxifen is used widely in the treatment of endocrine-responsive breast cancers in humans. Studies were undertaken to examine… (More)
Is this relevant?