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hydroxytamoxifen
Â
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1980-2017
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1980
2017
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Tamoxifen
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1955-2018
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hydroxytamoxifen
Tamoxifen
Papers overview
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Highly Cited
2009
Highly Cited
2009
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF.
Deo P. Pandey
,
Rosamaria Lappano
,
Lidia Albanito
,
Antonio Madeo
,
Marcello Maggiolini
,
Didier Picard
The EMBO journal
2009
The steroid hormone oestrogen can signal through several receptors and pathways. Although the transcriptional responses mediated…Â
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Highly Cited
2006
Highly Cited
2006
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells.
Adele Vivacqua
,
Daniela Bonofiglio
,
+4 authors
Marcello Maggiolini
Molecular endocrinology
2006
The growth of both normal and transformed epithelial cells of the female reproductive system is stimulated by estrogens, mainly…Â
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2005
2005
Neoadjuvant percutaneous 4-hydroxytamoxifen decreases breast tumoral cell proliferation: a prospective controlled randomized study comparing three doses of 4-hydroxytamoxifen gel to oral tamoxifen.
Philippe Rouanet
,
Gustavo Linares-Cruz
,
+8 authors
Thierry Maudelonde
Journal of clinical oncology : official journal…
2005
PURPOSE Two chemoprevention randomized studies using tamoxifen showed drug efficacy; however, adverse effects such as hot flushes…Â
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Highly Cited
1995
Highly Cited
1995
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.
B Le Douarin
,
Christian Zechel
,
+7 authors
Régine Losson
The EMBO journal
1995
Nuclear receptors (NRs) bound to response elements mediate the effects of cognate ligands on gene expression. Their ligand…Â
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1994
1994
Tamoxifen and hydroxytamoxifen as intramembraneous inhibitors of lipid peroxidation. Evidence for peroxyl radical scavenging activity.
José Barata Antunes Custódio
,
Teresa C. P. Dinis
,
L. Almeida
,
VÃtor M. C. Madeira
Biochemical pharmacology
1994
Tamoxifen (TAM) is the antiestrogen most widely used in the chemotherapy and chemoprevention of breast cancer. It has been…Â
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1993
1993
Identification of residues in the estrogen receptor that confer differential sensitivity to estrogen and hydroxytamoxifen.
Paul S. Danielian
,
Rachel L White
,
Samuel Hoare
,
Stephen E. Fawell
,
M. G. Parker
Molecular endocrinology
1993
We have generated mutant mouse estrogen receptors which differ in their sensitivity to estrogen and the antiestrogen 4…Â
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Highly Cited
1988
Highly Cited
1988
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer.
V Kumar
,
Pierre Chambon
Cell
1988
Extracts containing wild-type or mutant human estrogen receptor (ER) have been used to study the binding of ER to its responsive…Â
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1988
1988
Tamoxifen and hydroxytamoxifen isomers versus estradiol effects on normal human breast cells in culture.
Claude Malet
,
Axel van Gompel
,
+5 authors
Pierre Mauvais-Jarvis
Cancer research
1988
Estradiol and triphenylethylene antiestrogen actions have been studied extensively in breast cancer cell lines. However, their…Â
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Highly Cited
1986
Highly Cited
1986
Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture.
Yolande Berthois
,
Judith Katzenellenbogen
,
Benita S Katzenellenbogen
Proceedings of the National Academy of Sciences…
1986
Although much attention has been paid to the removal of hormones from sera and to the development of serum-free media for studies…Â
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Highly Cited
1984
Highly Cited
1984
Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
Benita S Katzenellenbogen
,
Michael Norman
,
Robert Eckert
,
S W Peltz
,
Walter F. Mangel
Cancer research
1984
Tamoxifen is used widely in the treatment of endocrine-responsive breast cancers in humans. Studies were undertaken to examine…Â
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