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hydroxymethylglutaryl-CoA synthase activity

Known as: acetoacetyl coenzyme A transacetase activity, (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity, HMG-CoA synthase activity 
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+). [EC:2.3.3.10, RHEA:10191]
National Institutes of Health

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Hydroxymethylglutaryl-CoA Synthase

Papers overview

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2011
2011
A Catalytic Approach to the Synthesis of (+)-Fluvastatin Analogue
E-mail: insukim@ulsan.ac.krReceived July 19, 2011, Accepted August 2, 2011Key Words : Fluvastatin, Asymmetric, Catalytic… 
1990
1990
Partial synthesis and antitubulin activity of minor colchicum alkaloids: N-acetoacetyl-deacetylcolchicine and 2-demethylspeciosine (speciocolchine).
Two minor Colchicum alkaloids, N-acetoacetyl-deacetylcolchicine [1] and 2-demethylspeciosine [7], were synthesized. The diacetate… 
1984
1984
Cholesterogenesis and related enzymes in isolated rat hepatocytes during pre‐ and postnatal life
Cholesterogenesis pathway during pre‐ and postnatal development was studied in isolated rat hepatocytes. No modified activity of… 
1973
1973
Immune response to chemically modified flagellin. IV. Further studies on the relationship between humoral and cell-mediated immunity.
1970
1970
Intrazelluläre Lokalisation von Enzymen des Flußkrebses
SummaryProperties of the mitochondria from the crayfish have been investigated. Buffered 0,1 M KCl with 0,001 M ATP proved to be… 
1968
1968
Acetoacetyl coenzyme A deacylase activity in liver mitochondria from fed and fasted rats.
1963
1963
The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid.
1962
1962
Reaction product of acetoacetyl coenzyme A and hydroxylamine.
1961
1961
Acetoacetate Formation from Acetoacetyl Coenzyme A in Rat Liver Mitochondria: Effect of Endocrine State and Nature of the System
1959
1959
Studies concerning the mechanism of action of acetoacetyl succinic thiophorase by use of O18.
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