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hydroxymethylglutaryl-CoA synthase activity

Known as: acetoacetyl coenzyme A transacetase activity, (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating) activity, HMG-CoA synthase activity 
Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+). [EC:2.3.3.10, RHEA:10191]
National Institutes of Health

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2017
2017
Production of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in plant seed oils has been pursued to improve… 
2011
2011
E-mail: insukim@ulsan.ac.krReceived July 19, 2011, Accepted August 2, 2011Key Words : Fluvastatin, Asymmetric, Catalytic… 
Highly Cited
2007
Highly Cited
2007
Thiolases are CoA-dependent enzymes which catalyze the formation of a carbon-carbon bond in a Claisen condensation step and its… 
1998
1998
Cytosolic 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) synthase catalyzes the formation of HMG‐CoA, the substrate for the rate… 
1975
1975
1. Two mitochondrial forms of acetoacetyl-CoA thiolases designated as enzyme A and enzyme B were crystallized from ox liver. They… 
1963