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hydropropidine

 
National Institutes of Health

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2 relations

Broader (2)

PhenanthridinesQuaternary Ammonium Compounds

Papers overview

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2019
2019
Are Hydroethidine-Based Probes Reliable for Reactive Oxygen Species Detection?
Abstract Detection and quantification of the highly reactive and short-lived superoxide (O•2−) can be challenging. Here, we… Expand
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2019
2019
High-Throughput Screening of NOX Inhibitors.
Development of new, selective inhibitors of nicotinamide adenine dinucleotide phosphate oxidase (NOX) isoforms is important both… Expand
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Review
2017
Review
2017
Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling.
In this review, some of the recent developments in probes and assay techniques specific for superoxide (O2-) and hydrogen… Expand
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2016
2016
Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation*
Using high throughput screening-compatible assays for superoxide and hydrogen peroxide, we identified potential inhibitors of the… Expand
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2014
2014
High-throughput Assays for Superoxide and Hydrogen Peroxide
Background: NADPH oxidases (Nox) are involved in pathogenesis of inflammatory and fibrotic diseases. Results: High-throughput… Expand
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Review
2014
Review
2014
HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes--the ultimate approach for intra- and extracellular superoxide detection.
BACKGROUND Nearly ten years ago, we demonstrated that superoxide radical anion (O2⋅¯) reacts with the hydroethidine dye (HE, also… Expand
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2013
2013
Hydropropidine: a novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide.
Here we report the synthesis and characterization of a membrane-impermeant fluorogenic probe, hydropropidine (HPr(+)), the… Expand
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