hybocarpone
National Institutes of Health
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The formal total synthesis of hybocarpone was achieved in eight steps from commercially available 1,2,4-trimethoxybenzene. Key…
The concise synthesis of the lichen-derived antitumor agent hybocarpone (1) and its analogs is described. A new synthetic…
Lichens are fungal and algal/cyanobacterial symbioses resulting in the production of specific metabolites. Some of these are…
Heterodermia hybocarponica Elix (from Australia and New Zealand) and H. queenslandica Elix (from tropical Australia) are…
The inhibitory effects of selected phenolic lichen substances were tested against a panel of methicillin- and multidrug-resistant…
A concise formal total synthesis of the cytotoxic bisnaphthazarin derivative hybocarpone has been completed through the…
The total synthesis of the lichen-derived antitumor agent hybocarpone (1) and related compounds is described. The successful…