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Highly pathogenic avian influenza (HPAI) H5N1 virus emerged in 1997 as a zoonotic disease in Hong Kong. It has since spread to… Expand Ebola virus disease (EVD) has been a great concern worldwide because of its high mortality. EVD usually manifests with fever… Expand Dengue virus is coated by an icosahedral shell of 90 envelope protein dimers that convert to trimers at low pH and promote fusion… Expand ABSTRACT Cellular entry of nonenveloped and enveloped viruses is often accompanied by dramatic conformational changes within… Expand Background: Cleavage of the influenza HA precursor by host proteases is a critical step in the virus life cycle. Results: The… Expand ![Graphic]
Poliovirus RNA (white) still gets into APCs that lack the right receptor.
Freigang/NASMHC class I molecules… Expand ![Graphic]
SecA helps proteins fold (right), unless they have a signal sequence (left).
Ehrmann/NASNew results from Markus… Expand The only confirmed mechanism for protein-mediated membrane fusion involves the formation of helix bundles, in which helices… Expand ABSTRACT Staphylococcus aureus is a versatile pathogen capable of causing life-threatening infections. Many of its cell wall and… Expand