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homoquinolinate

 
National Institutes of Health

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homoquinolinic acid

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2008
2008
Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes
N‐methyl‐d‐aspartate receptors (NMDARs) display differences in their sensitivity to the channel blockers Mg2+ and memantine that… Expand
Highly Cited
2005
Highly Cited
2005
Mechanism of Partial Agonism at NMDA Receptors for a Conformationally Restricted Glutamate Analog
The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site… Expand
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2004
2004
An investigation of NMDA receptor subunit pharmacology.
N-Methyl-D-aspartate (NMDA) receptors are critically involved in synaptic transmission, neural development and various forms of… Expand
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2002
2002
N‐Methyl‐d‐aspartate receptor subtype‐selectivity of homoquinolinate: an electrophysiological and radioligand binding study using both native and recombinant receptors
Homoquinolinate, a derivative of the endogenous NMDA agonist, quinolinate, has been shown to display higher affinity for Xenopus… Expand
1998
1998
[3H]Homoquinolinate Binds to a Subpopulation of NMDA Receptors and to a Novel Binding Site
Abstract: NMDA receptors mediate several important functions in the CNS; however, little is known about the pharmacology… Expand
Highly Cited
1997
Highly Cited
1997
Pharmacological heterogeneity of NMDA receptors: characterization of NR1a/NR2D heteromers expressed in Xenopus oocytes.
The pharmacology of recombinant NR1a/NR2D NMDA receptors expressed in Xenopus oocytes was examined and compared to the… Expand
Highly Cited
1994
Highly Cited
1994
The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition
The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and… Expand
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1984
1984
Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones
  • T. Stone
  • British journal of pharmacology
  • 1984
    • Corpus ID: 21130508
1 Various synthetic analogues of quinolinic acid have been tested for agonist and antagonist properties when applied by… Expand
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