homoquinolinate

N-methyl-d-aspartate receptors (NMDARs) display differences in their sensitivity to the channel blockers Mg(2+) and memantine… (More)

The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site… (More)

Both the nucleus accumbens (NAcc) and central amygdala (CeA) are thought to play roles in tolerance to, and dependence on, abused… (More)

Homoquinolinate, a derivative of the endogenous NMDA agonist, quinolinate, has been shown to display higher affinity for Xenopus… (More)

NMDA receptors mediate several important functions in the CNS; however, little is known about the pharmacology, biochemistry, and… (More)

The pharmacology of recombinant NR1a/NR2D NMDA receptors expressed in Xenopus oocytes was examined and compared to the… (More)

The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and… (More)

Various synthetic analogues of quinolinic acid have been tested for agonist and antagonist properties when applied by… (More)