homoquinolinate

N-methyl-d-aspartate receptors (NMDARs) display differences in their sensitivity to the channel blockers Mg(2+) and memantine… Expand

The NMDA ionotropic glutamate receptor is ubiquitous in mammalian central neurons. Because partial agonists bind to the same site… Expand

N-Methyl-D-aspartate (NMDA) receptors are critically involved in synaptic transmission, neural development and various forms of… Expand

Both the nucleus accumbens (NAcc) and central amygdala (CeA) are thought to play roles in tolerance to, and dependence on, abused… Expand

Homoquinolinate, a derivative of the endogenous NMDA agonist, quinolinate, has been shown to display higher affinity for Xenopus… Expand

NMDA receptors mediate several important functions in the CNS; however, little is known about the pharmacology, biochemistry, and… Expand

The pharmacology of recombinant NR1a/NR2D NMDA receptors expressed in Xenopus oocytes was examined and compared to the… Expand

The relationship between four pharmacologically distinct NMDA receptor subtypes, identified in radioligand binding studies, and… Expand

Various synthetic analogues of quinolinic acid have been tested for agonist and antagonist properties when applied by… Expand