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homogentisate 1,2-dioxygenase activity

Known as: homogentisic oxygenase activity, homogentisicase activity, homogentisate oxidase activity 
Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+). [EC:1.13.11.5, RHEA:15452]
National Institutes of Health

Papers overview

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2013
2013
Objectives : Yijin-tang has been used in the treatment of gastrointestinal diseases such as irritable bowel syndrome, gastritis… Expand
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2006
2006
SummaryAlkaptonuria is a rare, autosomal recessive metabolic disorder in which the homogentisic acid oxidase activity is absent… Expand
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1999
1999
Sinorhizobium meliloti strain N4 carries a Tn5luxAB insertion in a gene which is induced by nitrogen and carbon deprivation as… Expand
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1997
1997
The presence of homogentisic acid (HGA) in urine is diagnostic for alkaptonuria, a classical example of a biochemical lesion… Expand
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Highly Cited
1995
Highly Cited
1995
We report here the first characterization of a gene encoding a homogentisate dioxygenase, the Aspergillus nidulans hmgA gene. The… Expand
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Highly Cited
1994
Highly Cited
1994
Alkaptonuria (AKU; McKusick no. 203500) is a rare autosomal recessive disorder caused by the lack of homogentisic acid oxidase… Expand
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1983
1983
Mutations at the bwnA locus of Dictyostelium discoideum were found to result in drastically reduced levels of activity of the… Expand
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1976
1976
The growth retardation and external pathological lesions that occur in rats fed a 10% casein diet containing 5% tyrosine could be… Expand
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Review
1973
Review
1973
Alkaptonuria has been diagnosed in a laboratory born, five year old, female orangutan. In man, this relatively rare amino acid… Expand
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Review
1962
Review
1962
In 1908, Sir Archibald Garrod in his Croonian lectures coined the name 'inborn errors of metabolism' to describe a group of rare… Expand
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