homocamptothecin

Known as: hCPT 
 

Topic mentions per year

Topic mentions per year

1998-2018
02419982018

Papers overview

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2008
2008
Homocamptothecins (hCPTs) are a novel class of topoisomerase I (Top1) inhibitors with enhanced chemical stability compared with… (More)
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2004
2004
One activity potentially limiting the efficacy of camptothecin anticancer agents is their cellular efflux by the ATP-binding… (More)
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2002
2002
Topoisomerase I inhibitors of the camptothecin (CPT) family have emerged as potent clinical chemotherapeutic agents in first-line… (More)
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2001
2001
The homocamptothecin (hCPT) derivative BN80915 containing a seven-membered lactone ring represents one of the most potent… (More)
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2001
2001
BN 80915, a lead compound of the homocamptothecin (hCPT) family, has entered clinical trials. BN 80915 is a difluoro-hCPT where… (More)
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2000
2000
Homocamptothecin (hCPT), which differs from camptothecin (CPT) by the presence of an additional methylene group in the E-ring… (More)
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1999
1999
Homocamptothecin (hCPT) contains a seven-membered beta-hydroxylactone in place of the conventional six-membered alpha… (More)
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1999
1999
Homocamptothecin (hCPT) is a semisynthetic analogue of camptothecin (CPT) with a seven-membered beta-hydroxylactone resulting… (More)
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1999
1999
BN 80927, a novel homocamptothecin derivative, inhibits both topoisomerase I and topoisomerase II mediated DNA relaxation and… (More)
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1998
1998
Homocamptothecin (hCPT), a camptothecin (CPT) analogue with a seven membered beta-hydroxylactone which combines enhanced plasma… (More)
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