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homocamptothecin

Known as: hCPT 
 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Camptothecin
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies.
A magnetic nano-sized carrier for 10-hydroxycamptothecin (HCPT) was prepared by using Fe(3)O(4) nanoparticles as cores and… Expand
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2013
2013
Potential of in vitro reconstituted 3D human airway epithelia (MucilAir™) to assess respiratory sensitizers.
Respiratory sensitizers are considered as substances of higher risk, at the same level as carcinogens, mutagens and toxic… Expand
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Highly Cited
2011
Highly Cited
2011
MicroRNA 506 regulates expression of PPAR alpha in hydroxycamptothecin-resistant human colon cancer cells.
Chemotherapeutic drug resistance remains a major obstacle to the successful treatment of colon cancer. Here, we show that 77… Expand
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2011
2011
Hydroxycamptothecin-loaded Fe3O4 nanoparticles induce human lung cancer cell apoptosis through caspase-8 pathway activation and disrupt tight junctions.
10-Hydroxycamptothecin (HCPT) elicits strong anti-cancer effects and is less toxic than camptothecin (CPT), making it widely used… Expand
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2010
2010
Nanodiamonds as intracellular transporters of chemotherapeutic drug.
To explore the application of nanodiamonds (NDs) as anticancer drug delivery vehicles, firstly we examined the toxicity of NDs to… Expand
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2010
2010
Novel anti-tumor strategy: PEG-hydroxycamptothecin conjugate loaded transferrin-PEG-nanoparticles.
The aim of the study was to prepare transferrin modified stealth nanoparticles (Tf-PEG-NP) encapsulating poly(ethylene) glycol… Expand
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Highly Cited
2009
Highly Cited
2009
Covalently combining carbon nanotubes with anticancer agent: preparation and antitumor activity.
A multiwalled carbon nanotube (MWNT)-based drug delivery system was developed by covalently combining carbon nanotubes with the… Expand
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Highly Cited
2007
Highly Cited
2007
10-Hydroxycamptothecin loaded nanoparticles: preparation and antitumor activity in mice.
10-Hydroxycamptothecin (HCPT) loaded nanoparticles made from poly(caprolactone-co-lactide)-b-PEG-b-poly(caprolactone-co-lactide… Expand
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2007
2007
Preparation, characterization and biodistribution of the lactone form of 10-hydroxycamptothecin (HCPT)-loaded bovine serum albumin (BSA) nanoparticles.
10-Hydroxycamptothecin (HCPT) is insoluble in both water and physiological acceptable organic solvents and tends to change into… Expand
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2007
2007
siRNA-mediated Bcl-2 and Bcl-xl gene silencing sensitizes human hepatoblastoma cells to chemotherapeutic drugs.
1. The aim of the present study was to investigate the changes in chemotherapeutic drug sensitivity of HepG2 cells transfected… Expand
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