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histone methyltransferase complex

Known as: histone methyltransferase complex location 
A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins. [GOC:bf]
National Institutes of Health

Papers overview

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2018
2018
Epigenetic gene-regulation abnormalities have been implicated in various neuropsychiatric disorders including schizophrenia and… 
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Highly Cited
2011
Highly Cited
2011
A rare but deadly form of human pancreatic cancer harbors mutations in chromatin remodeling genes. Pancreatic neuroendocrine… 
Highly Cited
2011
Highly Cited
2011
H3K27 methylation mediated by the histone methyltransferase complex PRC2 is critical for transcriptional regulation, Polycomb… 
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2009
2009
Constitutive nuclear factor (NF)-κB activation in haematological malignancies is caused in several cases by loss of function… 
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Highly Cited
2009
Highly Cited
2009
While probing the role of RNA for the function of SET1C/COMPASS histone methyltransferase, we identified SET1RC (SET1 mRNA… 
Highly Cited
2007
Highly Cited
2007
The MLL family of histone methyltransferases maintains active chromatin domains by methylating histone H3 on lysine 4 (H3K4). How… 
Highly Cited
2005
Highly Cited
2005
CpG-binding protein (CXXC finger protein 1 (CFP1)) binds to DNA containing unmethylated CpG motifs and is required for mammalian… 
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Highly Cited
2004
Highly Cited
2004
ABSTRACT MLL (for mixed-lineage leukemia) is a proto-oncogene that is mutated in a variety of human leukemias. Its product, a… 
Highly Cited
2004
Highly Cited
2004
The cellular function of the menin tumor suppressor protein, product of the MEN1 gene mutated in familial multiple endocrine… 
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Highly Cited
2003
Highly Cited
2003
Recent experiments have demonstrated that the Polycomb group (PcG) gene EZH2 is highly expressed in metastatic prostate cancer…