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histone deacetylase 2

Known as: Transcriptional Regulator Homolog RPD3, HD2, HDAC2 
A histone deacetylase subtype that is found along with HISTONE DEACETYLASE 1; RETINOBLASTOMA-BINDING PROTEIN 4; and RETINOBLASTOMA-BINDING PROTEIN 7… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Alzheimer’s disease (AD) is characterized by progressive memory and neuronal loss culminating in cognitive impairment that not… Expand
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Highly Cited
2011
Highly Cited
2011
Transcription factor-based cellular reprogramming has opened the way to converting somatic cells to a pluripotent state, but has… Expand
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Highly Cited
2009
Highly Cited
2009
Persistent symptoms of depression suggest the involvement of stable molecular adaptations in brain, which may be reflected at the… Expand
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Highly Cited
2009
Highly Cited
2009
Chromatin modifications, especially histone-tail acetylation, have been implicated in memory formation. Increased histone-tail… Expand
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Highly Cited
2007
Highly Cited
2007
Histone deacetylases (HDACs) tighten chromatin structure and repress gene expression through the removal of acetyl groups from… Expand
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Highly Cited
2006
Highly Cited
2006
Glucocorticoids are the most effective antiinflammatory agents for the treatment of chronic inflammatory diseases even though… Expand
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Highly Cited
2005
Highly Cited
2005
Histone deacetylases (HDACs) 1 and 2 share a high degree of homology and coexist within the same protein complexes. Despite their… Expand
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Highly Cited
2004
Highly Cited
2004
Oxidative stress is a characteristic of chronic inflammatory diseases. The reactive oxygen intermediate hydrogen peroxide (H(2)O… Expand
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Highly Cited
1999
Highly Cited
1999
ATP-dependent nucleosome remodeling and core histone acetylation and deacetylation represent mechanisms to alter nucleosome… Expand
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Highly Cited
1997
Highly Cited
1997
Transcriptional repression by Mad-Max heterodimers requires interaction of Mad with the corepressors mSin3A/B. Sin3p, the S… Expand
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