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histone H3-K27 demethylation

Known as: H3K27 demethylation 
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone. [GOC:sp, PMID:20023638]
National Institutes of Health

Papers overview

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2018
2018
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma
High-throughput screening identified hypersensitivity of neuroblastomas to H3K27 demethylation inhibition. A different way to… Expand
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2017
2017
Inhibition of H3K27me3 Histone Demethylase Activity Prevents the Proliferative Regeneration of Zebrafish Lateral Line Neuromasts
The H3K27 demethylases are involved in a variety of biological processes, including cell differentiation, proliferation, and cell… Expand
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2017
2017
Glutamine metabolism regulates Th2 cell differentiation via the α-ketoglutalate-dependent demethylation of histone H3K27
The acquisition of T cell functions seems to be closely linked to the reprogramming of the metabolic pathway. However, the impact… Expand
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2015
2015
The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation.
Interleukin (IL) 17-producing T helper (Th17) cells play critical roles in the clearance of extracellular bacteria and fungi as… Expand
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2013
2013
The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.
Histone chaperones affect chromatin structure and gene expression through interaction with histones and RNA polymerase II (PolII… Expand
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