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histone H3-K27 demethylation

Known as: H3K27 demethylation 
The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone. [GOC:sp, PMID:20023638]
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma
High-throughput screening identified hypersensitivity of neuroblastomas to H3K27 demethylation inhibition. A different way to… 
2017
2017
Inhibition of H3K27me3 Histone Demethylase Activity Prevents the Proliferative Regeneration of Zebrafish Lateral Line Neuromasts
The H3K27 demethylases are involved in a variety of biological processes, including cell differentiation, proliferation, and cell… 
2017
2017
Glutamine metabolism regulates Th2 cell differentiation via the α-ketoglutalate-dependent demethylation of histone H3K27
The acquisition of T cell functions seems to be closely linked to the reprogramming of the metabolic pathway. However, the impact… 
Highly Cited
2015
Highly Cited
2015
The histone H3 lysine-27 demethylase Jmjd3 plays a critical role in specific regulation of Th17 cell differentiation.
Interleukin (IL) 17-producing T helper (Th17) cells play critical roles in the clearance of extracellular bacteria and fungi as… 
Highly Cited
2013
Highly Cited
2013
The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis
Histone chaperones affect chromatin structure and gene expression through interaction with histones and RNA polymerase II (PolII… 
2013
2013
MMSET dysregulates gene expression in myeloma through global and focal changes in H3K36 and H3K27 methylation
The MMSET (Multiple Myeloma SET domain) protein is overexpressed in multiple myeloma patients harboring the translocation t(4;14… 
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