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histamine secretion

The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle… Expand
National Institutes of Health

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Highly Cited
2001
Highly Cited
2001
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization.
Atopic diseases such as allergy and asthma are characterized by increases in Th2 cells and serum IgE antibodies. The binding of… Expand
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Highly Cited
1995
Highly Cited
1995
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.
Phosphatidylinositol (PI) 3-kinases have been implicated in several aspects of intracellular membrane trafficking, although a… Expand
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Highly Cited
1993
Highly Cited
1993
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.
The surface engagement of high affinity immunoglobulin E receptor (Fc epsilon RI) of rat basophilic leukemia 2H3 (RBL-2H3) cells… Expand
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Highly Cited
1985
Highly Cited
1985
Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of…
Incubation of rat mast cells with compound 48/80 resulted in transient breakdown of phosphatidylinositol 4,5-bisphosphate, rapid… Expand
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Highly Cited
1984
Highly Cited
1984
Mucosal mast cells. III. Effect of quercetin and other flavonoids on antigen-induced histamine secretion from rat intestinal mast cells.
Quercetin, a naturally occurring flavonol structurally related to the antiallergic drug disodium cromoglycate inhibits… Expand
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Highly Cited
1983
Highly Cited
1983
Activation of basophil and mast cell histamine release by eosinophil granule major basic protein
Major basic protein (MBP) is a primary constituent of eosinophil granules. In this report, we demonstrate that MBP from human… Expand
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Highly Cited
1982
Highly Cited
1982
Mucosal mast cells. II. Effects of anti-allergic compounds on histamine secretion by isolated intestinal mast cells.
Functional mast cells have been isolated from the lamina propria of the small intestine of rats infected with the nematode… Expand
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Review
1980
Review
1980
Calmodulin plays a pivotal role in cellular regulation.
The role of calcium ions (Ca2+) in cell function is beginning to be unraveled at the molecular level as a result of recent… Expand
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Highly Cited
1980
Highly Cited
1980
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein.
Cromolyn inhibited histamine release from mast cells that was induced by a classic secretagogue and correspondingly increased… Expand
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Highly Cited
1977
Highly Cited
1977
Effect of flavone inhibitors of transport ATPases on histamine secretion from rat mast cells
INTERACTION of multivalent ligands with receptors (immuno-globulin E, IgE) on the surface of the mast cell stimulates the calcium… Expand
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