histamine secretion

The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle… (More)
National Institutes of Health

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Highly Cited
2001
Highly Cited
2001
Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization.
Atopic diseases such as allergy and asthma are characterized by increases in Th2 cells and serum IgE antibodies. The binding of… (More)
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Highly Cited
1999
Highly Cited
1999
Neutrophil defensins induce histamine secretion from mast cells: mechanisms of action.
Defensins are endogenous antimicrobial peptides stored in neutrophil granules. Here we report that a panel of defensins from… (More)
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1999
1999
The mechanism of histamine secretion from gastric enterochromaffin-like cells.
Enterochromaffin-like (ECL) cells play a pivotal role in the peripheral regulation of gastric acid secretion as they respond to… (More)
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Highly Cited
1995
Highly Cited
1995
Mucosal histamine content and histamine secretion in Crohn's disease, ulcerative colitis and allergic enteropathy.
Histamine exhibits various biological effects in inflammatory and immunological reactions. To further define its potential role… (More)
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Highly Cited
1993
Highly Cited
1993
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.
The surface engagement of high affinity immunoglobulin E receptor (Fc epsilon RI) of rat basophilic leukemia 2H3 (RBL-2H3) cells… (More)
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1982
1982
Neurotensin stimulates exocytotic histamine secretion from rat mast cells and elevates plasma histamine levels.
1. Neurotensin stimulated histamine release and granule extrusion when applied to isolated rat peritoneal mast cells. 2. This… (More)
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1981
1981
Inhibition of histamine secretion from mast cells
Histamine secretion from mast cells may be inhibited by elevated intracellular levels of cyclic AMP and by several antiallergic… (More)
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Review
1980
Review
1980
Calmodulin plays a pivotal role in cellular regulation.
The role of calcium ions (Ca2+) in cell function is beginning to be unraveled at the molecular level as a result of recent… (More)
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Highly Cited
1980
Highly Cited
1980
Antiallergic drug cromolyn may inhibit histamine secretion by regulating phosphorylation of a mast cell protein.
Cromolyn inhibited histamine release from mast cells that was induced by a classic secretagogue and correspondingly increased… (More)
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1979
1979
Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells.
1. The concentration dependence on ATP of mast cell histamine secretion in the presence of various concentrations of Mg2+ and Ca2… (More)
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