hexosaminidase A activity

Known as: hexosaminidase A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
024619712017

Papers overview

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1999
1999
The severe neurodegenerative disorder, Tays-Sachs disease, is caused by a beta-hexosaminidase alpha-subunit deficiency which… (More)
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1999
1999
Sandhoff disease is a severe form of GM2 gangliosidosis that is caused by the deficiency of both hexosaminidase A and B. Startle… (More)
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1986
1986
Deficiency of hexosaminidase A (Hex A) in adults was found in 15 individuals from nine unrelated Ashkenazi families; 14… (More)
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1985
1985
We studied three patients from two unrelated families with adult hexosaminidase A deficiency. A 30-year-old, non-Jewish proband… (More)
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1984
1984
Six patients from three families developed adult GM2 gangliosidosis resulting from severe beta-hexosaminidase A deficiency. The… (More)
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1979
1979
Two adult sisters had spinocerebellar degeneration. Biochemical studies revealed a very low activity of both fraction A and… (More)
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1978
1978
Human kidney extracts heated to 60 degrees and devoid of hexosaminidase activity (2-acetamido-2-deoxy-beta-D-glucoside… (More)
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1978
1978
Because differences in hexosaminidase isoenzyme profiles of granulocytes and lymphoyctes suggested that such profiles might help… (More)
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1976
1976
To determine whether ligand-receptor interactions could engender the selective uptake by deficient cells of enzyme-laden… (More)
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1975
1975
In the course of screening for heterozygotes for beta-hexosaminidase deficiency, the serum and white cells of a clinically normal… (More)
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