heterochromatin-specific nonhistone chromosomal protein HP-1

Known as: HP1, Heterochromatin Protein-1, Heterochromatin Protein 1 
A protein family comprised of chromo and chromo shadow domain-containing, methyl-lysine binding proteins that are localized to heterochromatin. These… (More)

Topic mentions per year

Topic mentions per year

1989-2018
0204019892018

Papers overview

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Highly Cited
2006
Highly Cited
2006
Oct-3/4 is a POU domain homeobox gene that is expressed during gametogenesis and in early embryonic cells, where it has been… (More)
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Highly Cited
2005
Highly Cited
2005
Tri-methylation of histone H3 lysine 9 is important for recruiting heterochromatin protein 1 (HP1) to discrete regions of the… (More)
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Highly Cited
2005
Highly Cited
2005
Histones are subject to numerous post-translational modifications. Some of these 'epigenetic' marks recruit proteins that… (More)
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Highly Cited
2003
Highly Cited
2003
On the histone H3 tail, Lys 9 and Lys 27 are both methylation sites associated with epigenetic repression, and reside within a… (More)
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Highly Cited
2003
Highly Cited
2003
One function of heterochromatin is the epigenetic silencing by sequestration of genes into transcriptionally repressed nuclear… (More)
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Highly Cited
2001
Highly Cited
2001
Heterochromatin protein 1 (HP1) is localized at heterochromatin sites where it mediates gene silencing. The chromo domain of HP1… (More)
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Highly Cited
2001
Highly Cited
2001
In eukaryotic cells the histone methylase SUV39H1 and the methyl-lysine binding protein HP1 functionally interact to repress… (More)
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Highly Cited
2001
Highly Cited
2001
Members of the heterochromatin protein 1 (HP1) family are silencing nonhistone proteins. Here, we show that in P19 embryonal… (More)
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Highly Cited
1999
Highly Cited
1999
Krüppel-associated box (KRAB) domains are present in approximately one-third of all human zinc finger proteins (ZFPs) and are… (More)
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Highly Cited
1990
Highly Cited
1990
We report here that a point mutation in the gene which encodes the heterochromatin-specific nonhistone chromosomal protein HP-1… (More)
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