hepatocyte apoptotic process

Known as: hepatocyte apoptosis 
Any apoptotic process in a hepatocyte, the main structural component of the liver. [CL:0000182, GOC:jc, GOC:mtg_apoptosis, PMID:15856020]
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Recent research has suggested that apoptosis could be involved in the development of fibrosis, although it is… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES:The increasing incidence of nonalcoholic (NASH) and alcoholic steatohepatitis (ASH), associated with lack of effective… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Although apoptosis is a… (More)
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Highly Cited
2001
Highly Cited
2001
Tumor necrosis factor-alpha (TNF-alpha) contributes to liver injury by inducing hepatocyte apoptosis. Recent evidence suggests… (More)
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Highly Cited
2000
Highly Cited
2000
Mitochondrial cytochrome c release plays a critical role in apoptotic signal cascade after the activation of cell surface death… (More)
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Highly Cited
1999
Highly Cited
1999
Liver cirrhosis is the irreversible end result of fibrous scarring and hepatocellular regeneration, characterized by diffuse… (More)
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Highly Cited
1999
Highly Cited
1999
Cholestatic liver injury appears to result from the induction of hepatocyte apoptosis by toxic bile salts such as… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND & AIMS Cholestatic liver injury results from the intrahepatic accumulation of toxic bile salts. Toxic bile salt… (More)
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Highly Cited
1998
Highly Cited
1998
In acute liver injury induced by the injection of CCl4, cell death has been attributed to the necrosis of hepatocytes in the… (More)
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Highly Cited
1995
Highly Cited
1995
We investigated the role of hepatocyte apoptosis in four different murine models of acute inflammatory liver failure. Liver… (More)
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