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hemoregulatory peptide 5b

Known as: L-Lysine, N2-(N-(N-(N-(5-oxo-L-prolyl)-L-alpha-glutamyl)-L-alpha-aspartyl)-L-cysteinyl)-, SP1 pentapeptide, pyroglutamyl-glutamyl-aspartyl-cysteinyl-lysine 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Growth InhibitorsOligopeptidesPyrrolidonecarboxylic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Activated granulocytes oxidize the endogenous stem cell inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK) to the stimulatory dimer: a redox-mediated mechanism for demand-induced hematopoietic…
We have previously shown that the pentapeptide pGlu-Glu-Asp-Cys-Lys (pEEDCK), which is associated with mature leukocytes… 
1997
1997
Reduction in the duration of myelotoxicity associated with radioimmunotherapy with infusions of the hemoregulatory peptide, HP5b in mice
The hemoregulatory peptide, pGlu‐Glu‐Asp‐Cys‐Lys (pEEDCK or HP5b), has been shown to reversibly inhibit the proliferation of bone… 
1996
1996
Expression of G alpha 16, a G-protein alpha subunit specific for hematopoiesis in acute leukemia.
G-proteins are essential in signal transduction pathways. A G-protein alpha subunit termed G alpha 16 was found to be exclusively… 
Review
1995
Review
1995
Inhibitory peptides in hematopoiesis.
This paper will review the present knowledge on two small chemically unrelated peptides, the pentapeptide pGlu-Glu-Asp-Cys-Lys… 
1995
1995
Stem cell stimulation in vitro by the dekapeptide (pEEDCK)2: a single-factor alternative for multifactor cocktails.
Insertion of foreign genes into cellular DNA requires (at least one round of) DNA replication. Since hemopoietic stem cells do… 
1993
1993
Pre-CFU-S quiescence and stem cell exhaustion after cytostatic drug treatment: protective effects of the inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK).
Pre--CFU-S are characterized by their ability to generate spleen colony-forming cells (CFU-S) and by their ability to repopulate… 
1991
1991
Protection from arabinofuranosylcytosine and n-mustard-induced myelotoxicity using hemoregulatory peptide pGlu-Glu-Asp-Cys-Lys monomer and dimer.
We have previously shown that the synthetic peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK monomer) inhibits the cytostatic drug-induced… 
Review
1991
Review
1991
Haemoprotection against cytostatic drugs by stem cell inhibition.
1991
1991
Inhibition of Hematopoietic Stem Cell Proliferation by Hemoregulatory Peptide PyroGlu‐Glu‐Asp‐Cys‐Lys (pEEDCK) Provides Protection against Short‐Term Neutropenia and Long‐Term Damage a
Hematological damage is the main general problem in the therapy of malignant tumors with cytostatic substances. Part of the… 
1990
1990
Hemoregulatory peptide pGlu-Glu-Asp-Cys-Lys: a new synthetic derivative for avoiding dimerization and loss of inhibitory activity.
The hemoregulatory peptide (pGlu-Glu-Asp-Cys-Lys, pEEDCK) is a potent inhibitor of stem cell recruitment, which is a major source… 
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