heme catabolic process

Known as: haem catabolism, heme catabolism, haem catabolic process 
The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring. [GOC:jl]
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Heme oxygenase-1 (HO-1) is a key cytoprotective, antioxidant, and antiinflammatory molecule. The pathophysiological functions of… (More)
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Highly Cited
2004
Highly Cited
2004
Biliverdin, a product of heme oxygenase-1 (HO-1) enzymatic action, is converted into bilirubin, which has been considered a waste… (More)
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Review
2003
Review
2003
The microsomal heme oxygenase system consists of heme oxygenase (HO) and NADPH-cytochrome P450 reductase, and plays a key role in… (More)
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Highly Cited
2003
Highly Cited
2003
Heme oxygenase 1 (HO-1) catalyzes heme breakdown, eventually releasing iron, carbon monoxide, and bilirubin IXalpha. HO-1 is… (More)
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Highly Cited
2002
Highly Cited
2002
Heme oxygenase is a rate-limiting enzyme in heme degradation, leading to the generation of free iron, biliverdin, and carbon… (More)
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Highly Cited
2001
Highly Cited
2001
Bilirubin, the end product of heme catabolism, is taken up from the blood circulation into the liver. This work identifies a high… (More)
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Review
1999
Review
1999
Zinc protoporphyrin (ZnPP) is a normal metabolite that is formed in trace amounts during heme biosynthesis. The final reaction in… (More)
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Highly Cited
1997
Highly Cited
1997
Heme catabolic processes produce the antioxidants biliverdin and bilirubin, as well as the potent prooxidant free iron. Since… (More)
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Highly Cited
1997
Highly Cited
1997
Oxidative stress has been suggested to be involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer disease… (More)
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Highly Cited
1991
Highly Cited
1991
Oxidized low density lipoprotein (LDL), formed in vivo from presently unknown reactions, may play a role in atherogenesis. In… (More)
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