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hemantane

 
National Institutes of Health

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Broader (1)

Adamantane
analogs & derivatives

Papers overview

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2019
2019
Comparative Assessment of the Effectiveness of Noncompetitive NMDA Receptor Antagonists Amantadine and Hemantane in Morphine Withdrawal Syndrome Model
Activities of noncompetitive NMDA receptor antagonists (aminoadamantane derivatives) were assessed in random-bred rats with… Expand
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2017
2017
Non-Competitive NMDA Receptor Antagonist Hemantane Reduces Ethanol Consumption in Long-Term Alcohol Experienced Rats
Activity of hemantane, an amino adamantane derivative, exhibiting the properties of lowaffinity non-competitive NMDA receptor… Expand
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2016
2016
Comparison of the Analgesic Activity of Antiparkinsonian Aminoadamantane Derivatives Amantadine and Hemantane
The efficacy of some aminoadamantane derivatives used as neurodegeneration treatments is due to their ability to block NMDA… Expand
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2015
2015
Anti-Parkinsonian Activity of Hemantane on a Model of Hemiparkinsonian Syndrome in Rats
Hemantane demonstrated a pronounced antiparkinsonian activity in the model of hemiparkinsonian syndrome provoked in rats by… Expand
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2014
2014
Anti-Inflammatory Activity of Hemantane on Peripheral Inflammation and Lipopolysaccharideinduced Neuro-Inflammation Models
Hemantane is a novel antiparkinsonian drug that is undergoing clinical trials. Hemantane in the dosage range 10 – 40 mg/kg… Expand
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2013
2013
The activity of antiparkinsonian drug hemantane in models of peripheral inflammation and lipopolysaccharide-induced neuroinflammation
A large body of literature supports the idea that inflammation exacerbates neurodegenerative pathology. This idea is also… Expand
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2011
2011
[Comparative study of amantadine and hemantane effects on development of levodopa-induced dyskinesia in rat model of parkinsonian syndrome].
Chronic administration of levodopa and benserazide (10 and 15 mg/kg, respectively) cause the development of dyskinesia in rats… Expand
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2011
2011
[Influence of hemantane and doxycycline on MPTP-evoked behavior violations in C57BL/6 mice].
The effects of anti-parkinsonian drug hemantane [(2-adamantyl)hexamethylenimine] (10 mg/kg, p. o.) and/or antibiotic drug… Expand
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2008
2008
[Effects of hemantane on the main subtypes of dopamine receptors in the rat striatum ex vivo].
The effect of the antiparkinsonian drug hemantane on various subtypes of dopamine receptors in the striatum of Wistar rats have… Expand
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2007
2007
Study of auto- and heteroreceptor components of the presynaptic dopamine reuptake modulation in the mechanism of the in vitro action of the novel antiparkinsonian drug hemantane
The effect of Hemantane, a new 2-aminoadamantane derivative (N-adamant-2-ylhexamethylenimine hydrochloride) with antiparkinsonian… Expand
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