hemantane

Activity of hemantane, an amino adamantane derivative, exhibiting the properties of lowaffinity non-competitive NMDA receptor… (More)

The efficacy of some aminoadamantane derivatives used as neurodegeneration treatments is due to their ability to block NMDA… (More)

Hemantane demonstrated a pronounced antiparkinsonian activity in the model of hemiparkinsonian syndrome provoked in rats by… (More)

Hemantane is a novel antiparkinsonian drug that is undergoing clinical trials. Hemantane in the dosage range 10 – 40 mg/kg… (More)

A large body of literature supports the idea that inflammation exacerbates neurodegenerative pathology. This idea is also… (More)

A single intraperitoneal injection of MPTP neurotoxin (30 mg/kg) in C57BL/6 mice causes desynchronization of EEG with a decrease… (More)

Chronic administration of levodopa and benserazide (10 and 15 mg/kg, respectively) cause the development of dyskinesia in rats… (More)

The pharmacokinetics ofhemantane after administration in different ways has been studied in rats. It is established that… (More)

The effects of anti-parkinsonian drug hemantane [(2-adamantyl)hexamethylenimine] (10 mg/kg, p. o.) and/or antibiotic drug… (More)

The effect of the antiparkinsonian drug hemantane on various subtypes of dopamine receptors in the striatum of Wistar rats have… (More)