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heart valve development

Known as: cardiac valve development 
The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
In vertebrates, heart pumping is required for cardiac morphogenesis and altering myocardial contractility leads to abnormal… Expand
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2015
2015
Cardiac valve structure and function are primarily determined during early development. Consequently, abnormally-formed heart… Expand
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Highly Cited
2014
Highly Cited
2014
Currently available heart valve replacements are limited in long-term performance or fail due to leaflet thickening, lack of… Expand
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Review
2012
Review
2012
Congenital heart defects affect approximately 1–5 % of human newborns each year, and of these cardiac defects 20–30 % are due to… Expand
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Highly Cited
2011
Highly Cited
2011
We report that the dominant human missense mutations G303E and G296S in GATA4, a cardiac-specific transcription factor gene… Expand
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Highly Cited
2010
Highly Cited
2010
Wnt signaling mediated by beta-catenin has been implicated in early endocardial cushion development, but its roles in later… Expand
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Highly Cited
2010
Highly Cited
2010
Valvular heart disease (VHD) is the term given to any disease process involving one or more of the heart valves. The condition… Expand
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Highly Cited
2009
Highly Cited
2009
The directionality of local blood flow in the zebrafish embryonic heart is essential for proper heart valve formation. 
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Highly Cited
2009
Highly Cited
2009
Rationale: NFATc1 (nuclear factor of activated T-cells cytoplasmic 1) activity in endocardial cushion (ECC) endothelial cells is… Expand
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Highly Cited
2007
Highly Cited
2007
Heart valve structures derived from mesenchymal cells of the endocardial cushions (ECs) are composed of highly organized cell… Expand
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